临床输血与检验2018,Vol.20Issue(2):180-181,201,3.DOI:10.3969/j.issn.1671-2587.2018.02.022
手足口病患儿免疫球蛋白及补体C3、C4检测及意义
Clinical Significance of Immunoglobulins and Complements 3 and 4 in Children with Hand-Foot-Mouth Virus Infection
摘要
Abstract
Objective To detect immunoglobulins and C3 and C4 in children with hand-foot-mouth disease so as to evaluate the immune status of the patients. Methods One hundred and two cases of children with hand-foot-mouth disease, including 47 cases of mild manifestations 55 cases of severe manifestations and 30 cases of healthy children Serum IgA, IgG,IgM,C3,and C4 levels were examined. Results A statistical significance (P<0.05) was noted among the three groups of children,and the child patients presented high levels of IgM and IgG antibodies compared with the healthy control. IgA,C3,and C4 levels was lower than those of healthy children. Conclusion The immune status of children with hand-foot-mouth disease produced a remarkable immunity against the virus infection,which may help for the early diagnosis and clinical managements.关键词
手足口病/免疫球蛋白/补体Key words
Hand-foot–mouth disease/ Immunoglobulin/ Complements分类
医药卫生引用本文复制引用
翟慢慢,周崇臣,宋继军,李巍,田冬冬..手足口病患儿免疫球蛋白及补体C3、C4检测及意义[J].临床输血与检验,2018,20(2):180-181,201,3.基金项目
本课题受河南省自然科学基金项目(No.152300410002)资助 (No.152300410002)