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手足口病患儿免疫球蛋白及补体C3、C4检测及意义

翟慢慢 周崇臣 宋继军 李巍 田冬冬

临床输血与检验2018,Vol.20Issue(2):180-181,201,3.
临床输血与检验2018,Vol.20Issue(2):180-181,201,3.DOI:10.3969/j.issn.1671-2587.2018.02.022

手足口病患儿免疫球蛋白及补体C3、C4检测及意义

Clinical Significance of Immunoglobulins and Complements 3 and 4 in Children with Hand-Foot-Mouth Virus Infection

翟慢慢 1周崇臣 1宋继军 1李巍 1田冬冬1

作者信息

  • 1. 450000 郑州大学附属儿童医院,河南省儿童医院,郑州儿童医院
  • 折叠

摘要

Abstract

Objective To detect immunoglobulins and C3 and C4 in children with hand-foot-mouth disease so as to evaluate the immune status of the patients. Methods One hundred and two cases of children with hand-foot-mouth disease, including 47 cases of mild manifestations 55 cases of severe manifestations and 30 cases of healthy children Serum IgA, IgG,IgM,C3,and C4 levels were examined. Results A statistical significance (P<0.05) was noted among the three groups of children,and the child patients presented high levels of IgM and IgG antibodies compared with the healthy control. IgA,C3,and C4 levels was lower than those of healthy children. Conclusion The immune status of children with hand-foot-mouth disease produced a remarkable immunity against the virus infection,which may help for the early diagnosis and clinical managements.

关键词

手足口病/免疫球蛋白/补体

Key words

Hand-foot–mouth disease/ Immunoglobulin/ Complements

分类

医药卫生

引用本文复制引用

翟慢慢,周崇臣,宋继军,李巍,田冬冬..手足口病患儿免疫球蛋白及补体C3、C4检测及意义[J].临床输血与检验,2018,20(2):180-181,201,3.

基金项目

本课题受河南省自然科学基金项目(No.152300410002)资助 (No.152300410002)

临床输血与检验

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1671-2587

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