环境与职业医学2018，Vol.35Issue(3)：246-252,7.DOI:10.13213/j.cnki.jeom.2018.17543
生物样品中多溴联苯醚及其代谢物检测方法的研究进展
Research progress on detection methods for polybrominated diphenyl ethers and their metabolites in biological samples
摘要
Abstract
Polybrominated diphenyl ethers (PBDEs),as additive brominated flame retardants,are widely used in a variety of industrial and commercial products.PBDEs are persistent organic pollutants with environmental endocrine disruption effect,neurotoxicity,and reproductive toxicity.PBDEs can be metabolized into hydroxylated PBDEs (OH-PBDEs) and methylated into methoxylated PBDEs (MeO-PBDEs) in vivo.Recently,PBDEs and their metabolites (OH-PBDEs,MeO-PBDEs) and bromophenols have raised social concerns due to the detection of above-mentioned chemicals in environment and organisms.In this review,the exposure levels and the methods of pretreatment and detection of PBDEs and their metabolites in environment and human body were summarized,aiming to provide methodological references for the exposure assessment and toxicological research of PBDEs.关键词
多溴联苯醚/羟基多溴联苯醚/甲氧基多溴联苯醚/多溴苯酚/检测方法/生物样本Key words
polybrominated diphenyl ethers/hydroxylated PBDEs/methoxylated PBDEs/bromophenol/detection method/biological sample分类
医药卫生引用本文复制引用
季洁云,冯超,卢大胜,汪国权,栾洋,许浩..生物样品中多溴联苯醚及其代谢物检测方法的研究进展[J].环境与职业医学,2018,35(3):246-252,7.基金项目
国家自然科学基金项目(编号:21477078) （编号:21477078）
