实用妇产科杂志2018，Vol.34Issue(3)：203-207,5.
早期宫颈癌淋巴脉管间隙浸润与临床病理因素及预后的关系
Relationship among Lymph Vascular Space Invasion with Clinicopathological Factors and Prognosis in Early Cervical Cancer
周滢 1姜继勇1
作者信息
- 1. 大连医科大学附属大连市妇产医院,辽宁大连116033
- 折叠
摘要
Abstract
Objective:To investigate the relationship among lymph vascular space invasion (LVSI) with clinicopathological factors and prognosis in early cervical cancer(CC).Methods:Retrospective analysis was conducted on 280 cases of early CC that were surgically treated at Dalian Maternal and Child Health Care hospital between January 2009 and June 2012.Univariate analysis was performed to study the relationship between LVSI and clinicopathological factors,the clinicopathological factors statistically associated with LVSI in univariate analysis were studied by multivariate analysis to identify the independent risk factors of LVSI.Results:①Univariate analysis showed that histological type,histological differentiation,lymph node metastasis and cervical stromal invasion depth were significantly correlated with LVSI (P ＜ O.05).Multivariate analysis showed that LVSI was an independent risk factor for differentiation,lymph node metastasis,and the depth of invasion.②The 5-year disease free survival(DFS) of LVSI positive patients was 74％,and the overall survival(OS) was 80％.The 5-year DFS and OS of LVSI negative patients were 93％ (P ＜ 0.05).Conclusions:LVSI can reflect the potential risk of lymph node metastasis to some extent.LVSI is the independent risk factor of lymph node metastasis and can significantly reduce the DFS and OS.Patients with LVSI positive may have deeper infiltration and poorer differentiation,but more studies are needed to confirm it.关键词
宫颈癌/淋巴脉管间隙浸润/淋巴结转移/临床病理因素Key words
Cervical carcinoma/Lymph vascular space invasion/Lymph node metastasis/Clinicopathological factors分类
医药卫生引用本文复制引用
周滢,姜继勇..早期宫颈癌淋巴脉管间隙浸润与临床病理因素及预后的关系[J].实用妇产科杂志,2018,34(3):203-207,5.
