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黄芩素对糖尿病周围神经病变保护作用机制研究进展

王星 李彩娜 申竹芳

中国临床药理学杂志2018,Vol.34Issue(1):70-72,76,4.
中国临床药理学杂志2018,Vol.34Issue(1):70-72,76,4.DOI:10.13699/j.cnki.1001-6821.2018.01.019

黄芩素对糖尿病周围神经病变保护作用机制研究进展

Advances on the protective mechanism study of baicalein on diabetic peripheral neuropathy

王星 1李彩娜 1申竹芳1

作者信息

  • 1. 中国医学科学院、北京协和医学院药物研究所天然药物活性物质与功能国家重点实验室,北京100050
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摘要

Abstract

Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes,and is also the main cause of diabetic disability.Presently,there are more and more people suffering from DPN,so it is of great significance to further explore the pathogenesis and develop new drugs for the treatment of DPN.Baicalein has many biological functions,such as anti-inflammation,anti-allergy,anti-oxidative stress,anti-tumor,anti-bacteria,anti-thrombosis and protection of liver,heart and brain,neurons and so on.Previous studies have shown that baicalein has some preventive and therapeutic effects on DPN.Thus,this article makes a review of the achievements on protective mechanism studies of baicalein on DPN.

关键词

黄芩素/糖尿病/糖尿病慢性并发症/糖尿病周围神经病变/作用机制

Key words

baicalein/diabetes/diabetic chronic complication/diabetic peripheral neuropathy/mechanism of action

分类

医药卫生

引用本文复制引用

王星,李彩娜,申竹芳..黄芩素对糖尿病周围神经病变保护作用机制研究进展[J].中国临床药理学杂志,2018,34(1):70-72,76,4.

基金项目

中国医学科学院医学与健康科技创新工程基金资助项目(2016-I2M-2-006) (2016-I2M-2-006)

中国临床药理学杂志

OA北大核心CSCDCSTPCD

1001-6821

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