中国临床医学影像杂志2018，Vol.29Issue(3)：177-181,5.
全模型迭代重建算法(IMR)在“双低”冠状动脉CTA成像中应用价值的探讨
Investigation of iterative model reconstruction in coronary CTA with low dose and low Iodine load
摘要
Abstract
Objective:To investigate the clinical value of IMR technique in 256 slice prospective coronary CTA with low dose and low Iodine load.Methods:One hundred patients who would perform coronary CTA were enrolled and the patients were divided into two groups randomly.All the patients were performed prospective CTA.Patients in group A were performed CTA by using normal tube voltage(120 kV),dose right index(DRI)=15 was considered to be currents and iDose4 reconstruction.Patients in group B were performed CTA by using low tube voltage (100kV),DRI=11 was considered to be currents and IMR reconstruction.The injection protocols of group A and group B were 0.8 mL/kg and 0.6 mL/kg,respectively.The injection time was 12 seconds.Quantitative measurements of CT value,image noise,signal-to-noise (SNR) and contrast-to-noise (CNR) were measured in each group.t-test was used for comparisons of objective evaluation,indices(noise,SNR,CNR),radiation dose(CTDIvol,DLP,ED) and Iodine load between the two groups.Mann-Whitney U test was used for comparisons of subjective evaluation of IQ between the two groups.A level of P＜0.05 was considered statistically significant.Results:There were significant differences in SD between group A(34.3±4.3)HU and group B(23.4±2.8)HU(t=14.977,P=0.000).There were significant differences in SNR between group A (11.9±1.9) and group B (16.3±2.2)(t=-10.713,P=0.000).There were significant differences in CNR between group A(15.1±2.3) and group B(21.1±2.7)(t=-12.083,P=0.000).Group B showed the better objective data.Compared with group A,there were significant differences in subjective noise and acceptability of images (U=951.000,934.000,P=0.008,0.005).There were no significant differences in image contrast and image sharpness (U=1 233.000,1 233.500,P=0.884,0.888).The effective dose(ED) of group B (0.94±0.23)mSv was 39％ lower than that of group A (1.53±0.32)mSv.The Iodine load of group B (15.1±2.4)g was 25％ lower than that of group A (20.1±2.5)g.Conclusion:Compared with iDose4,using 256 MDCT,iterative model reconstruction technique can provide 39％ ED and 25％ Iodine load reduction,while the images could still satisfy the requirement of diagnosis.关键词
冠状动脉疾病/辐射剂量/体层摄影术,螺旋计算机/冠状血管造影术Key words
Coronary disease/Radiation dosage/Tomography, spiral computed/Coronary angiography分类
医药卫生引用本文复制引用
高思喆,马跃,侯阳,张晓娟..全模型迭代重建算法(IMR)在“双低”冠状动脉CTA成像中应用价值的探讨[J].中国临床医学影像杂志,2018,29(3):177-181,5.基金项目
国家自然科学基金:81301221 （）
辽宁省高等学校创新团队支持计划:LT2014017. （）
