中成药2018，Vol.40Issue(3)：583-586,4.DOI:10.3969/j.issn.1001-1528.2018.03.014
氮酮对6-姜酚透皮吸收的影响
Effect of azone on transdermal absorption of 6-gingerol
孙权 1李冰 1王星 1祝妍 1王星皓 1陈再兴1
作者信息
- 1. 中国医科大学药学院,辽宁沈阳110122
- 折叠
摘要
Abstract
AIM To study the effect of azone on transdermal absorption of 6-gingerol.METHODS In vitro transdermal diffusion test was performed by TP-6 horizontal diffusion pool.In vitro rat skins were selected as permeation barrier,the effects of different concentrations of ethanol and azone on permeation performance of 6-gingerol were investigated.RESULTS Both 30％ ethanol and 3％ azone contributed to the significant permeation enhancement of 6-gingerol.CONCLUSION This research can provide reference for the preparation of transdermal drug delivery systems containing 6-gingerol.关键词
氮酮/6-姜酚/透皮吸收Key words
azone/6-gingerol/transdermal absorption分类
医药卫生引用本文复制引用
孙权,李冰,王星,祝妍,王星皓,陈再兴..氮酮对6-姜酚透皮吸收的影响[J].中成药,2018,40(3):583-586,4.
