北京中医药大学学报2018，Vol.41Issue(4)：342-348,7.DOI:10.3969/j.issn.1006-2157.2018.04.013
代谢综合征痰证与非痰证人群的证素兼杂特征研究及痰证相关理化指标分析
Concurrent pattern elements in patients with non-phlegm or phlegm pattern of metabolic syndrome and physiochemical parameters related to phlegm pattern
摘要
Abstract
Objective To analyze the characteristics of concurrent pattern elements of the patients with phlegm or non-phlegm pattern in metabolic syndrome, explore the correlation between different disease locations as well as complicated diseases and physicochemical parameters in patients with metabolic syndrome, and to provide a theoretical basis for the early detection, diagnosis and treatment of the disease. Methods The 2005 International Diabetes Federation diagnostic criteria and pattern element differentiation method were used to select 334 patients of metabolic syndrome with phlegm pattern and 288 patients of metabolic syndrome with non-phlegm pattern into this study. Physical and chemical parameters and TCM four diagnostic data were entered and analyzed with SPSS 20.0 to explore characteristics of concurrent pattern elements of phlegm and non-phlegm patterns in patients with metabolic syndrome,and to explore the correlation between different locations as well as complicated diseases and physicochemical parameters in patients of metabolic syndrome. Results 1.Disease locations of liver, spleen, kidney, lung,gallbladder, stomach distributed in phlegm group were more frequent than those in non-phlegm group;the percentage of patients with dampness, fever, qi stagnation, blood stasis, qi deficiency, yin deficiency,yang deficiency and blood deficiency were higher than those in non-phlegm group. 2.In male patients with phlegm pattern, the frequency of disease location in the liver was lower than that in the spleen and stomach,while the female patients had opposite distribution. The age of the liver and spleen groups were less than the age in the kidney group among patients with phlegm pattern. 3. In phlegm-pattern patients,the frequency of blood deficiency pattern among male patients was lower than that of qi deficiency,yin deficiency and yang deficiency patterns, while the frequency of females was higher than those of the three groups. The levels of uric acid (UA) and creatinine (Cr) in yang-deficiency pattern group were higher than those in blood deficiency pattern group. Cr levels in yin deficiency pattern group were also higher than those in blood deficiency pattern group. Conclusions Disease locations of phlegm pattern group in metabolic syndrome were: liver, spleen, kidney, lung, gallbladder, stomach and miscellaneous diseases were dampness,heat,qi stagnation, blood stasis, qi deficiency, yin deficiency, yang deficiency, and blood deficiency; Non-phlegm pattern group presented no concurrent pattern element characteristics. Disease locations were in the stomach in the male while they were changed to the liver in the female. Concurrent pattern elements was blood deficiency in patients of phlegm pattern in metabolic syndrome. In addition, the order of disease location of metabolic syndrome patients with phlegm pattern was spleen,liver and kidney. There was a correlation between yin-yang disharmony and levels of UA and Cr.关键词
代谢综合征/痰证/证素兼杂/理化指标Key words
metabolic syndrome/phlegm pattern/mixed pattern elements/physiochemical indexes分类
医药卫生引用本文复制引用
张梦婷,林雪娟,王永发,俞洁,熊红萍,高碧珍..代谢综合征痰证与非痰证人群的证素兼杂特征研究及痰证相关理化指标分析[J].北京中医药大学学报,2018,41(4):342-348,7.基金项目
国家自然科学基金项目(No.81273666),福建省中医药科研项目(No.wztn201309),国家中医药管理局资助项目 National Natural Science Foundation of China(No.81273666),TCM Scientific Research Foundation of Fujian Province(No.wztn201309),Project supported by State Administration of Traditional Chinese Medicine of China （No.81273666）
