大学化学2018，Vol.33Issue(3)：1-10,10.DOI:10.3866/PKU.DXHX201711038
核药物发展小记
Nuclear Medicine: The Synergy of Radiochemistry and Molecular Medicine
摘要
Abstract
The major progresses of nuclear medicine since 1970s are briefly reviewed. This mini-review is mainly focused on the development of [18F]2-fluoro-2-deoxy-D-glucose ([18F]FDG), which is the most widely applied PET tracer in clinic diagnosis. The investigation of [18F]FDG dated back to 1920s and was finally applied to the clinic after almost half century. [18F]FDG has been of great importance in the diagnosis of tumor, neurodegenerative diseases and cardiovascular diseases ever since. Except from [18F]FDG, the state-of-art development in peptide and protein nuclear medicines is also introduced. Along with the course of the development of nuclear medicine, several scientists who have made a great contribution to nuclear medicine are also introduced and paid at the same time with our sincere respect. With these introductions above, the authors intend to demonstrate the unique characteristic of nuclear medicine based on basic research and oriented to clinic problems. At last, the authors sincerely hope that the readers could be inspired on their own scientific researches after getting an insight into the history of classic nuclear medicines.关键词
核药物/正电子发射断层扫描成像/应用化学Key words
Nuclear medicine/Positron emission tomography imaging/Applied chemistry分类
社会科学引用本文复制引用
李聪,刘慧,韩宇翔,刘志博..核药物发展小记[J].大学化学,2018,33(3):1-10,10.基金项目
国家自然科学基金(21778003) （21778003）
