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持续肾脏替代治疗时机对感染性休克合并急性肾损伤患者预后的影响

殷静静 郑瑞强 林华 邵俊

实用临床医药杂志2018,Vol.22Issue(7):63-66,4.
实用临床医药杂志2018,Vol.22Issue(7):63-66,4.DOI:10.7619/jcmp.201807017

持续肾脏替代治疗时机对感染性休克合并急性肾损伤患者预后的影响

Influence of initiation timing of continuous renal replacement therapy on prognosis of patients with septic shock and acute kidney injury

殷静静 1郑瑞强 1林华 1邵俊1

作者信息

  • 1. 江苏省苏北人民医院重症医学科,江苏扬州,225001
  • 折叠

摘要

Abstract

Objective To investigate the influence of initiation timing of continuous renal replacement therapy(CRRT) on prognosis of patients with septic shock and acute kidney injury,and its risk factors for death.Methods A total of 63 cases with septic shock and acute kidney injury (AKI) that reaching diagnostic criteria for failure in ICU of our hospital were randomly divided into two groups according to initiation timing,the early group (n =33) started CRRT with in 12 h and late group (n =30) started 48 h.The survival rate of two groups were compared,Cox regression analysis was performed to evaluate the risk factors of death.Results There were no significant difference in age,surgery condition,medical history and severity of disease between two groups before treatment.Log-Rank test shoed no significant difference in survival rate (P =0.574).Cox regression analysis showed that blood lactate and APACHE I scores were the independent risk factors of prognosis.Conclusion Timing of CRRT has no effect on patients with septic shock and acute kidney injury.

关键词

急性肾衰竭/感染性休克/肾脏替代治疗/治疗时机/预后

Key words

acute kidney injury/septic shock/continuous renal replacement therapy/timing/prognosis

分类

医药卫生

引用本文复制引用

殷静静,郑瑞强,林华,邵俊..持续肾脏替代治疗时机对感染性休克合并急性肾损伤患者预后的影响[J].实用临床医药杂志,2018,22(7):63-66,4.

实用临床医药杂志

1672-2353

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