中国临床保健杂志2018，Vol.21Issue(2)：168-171,4.DOI:10.3969/J.issn.1672-6790.2018.02.007
检测子宫上皮细胞游离亚铁原卟啉与人类乳头瘤病毒在宫颈癌筛查中的价值
The clinical values of cells free ferrous protoporphyrin and high-risk HPV examination in the screening of cer-vical carcinoma
摘要
Abstract
Objective To investigate clinical values of cells free ferrous protoporphyrin examination in the screening of cervical carcinoma.Methods A retrospective analysis of data from January 2016 to November 2017 with FH examination of 120 cases were proved by cervical pathological examination in Anhui Provincial Hospital.The pathol-ogy results as the gold standard for diagnosis,the sensitivity,specificity,positive predictive value,negative predictive val-ue,accuracy positive and negative likelihood ratio and AUC of FH detection,LCT detection and HPV detection were cal-culated in the screening of cervical cancer.Results 120 cases underwent FH detection,HPV detection and pathological examination,the sensitivity of FH test was 76.47%,specificity was 78.26%,accuracy was 77.50%,positive predictive value was 72.22%,negative predictive value was 81.82%,positive likelihood ratio was 351.76%,negative likelihood ratio was 30.07%,AUC was 0.774;HPV 70.59%specificity of sensitivity test results was 73.91% and accuracy rate was 72.50%,the positive predictive value was 66.67%and negative predictive value was 77.27%,the positive likeli-hood ratio was 270.59%,negative likelihood ratio was 39.79%,AUC was 0.723.Conclusions The sensitivity of FH examination is similar to that of LCT and high-risk HPV.It has certain clinical value in the screening of cervical carcinoma.关键词
宫颈肿瘤/细胞微环境/临床实验室技术/血红素/乳头状瘤病毒科Key words
Uterine cervical neoplasms/Cellular microenvironment/Clinical laboratory techniques/Heme/Papil-lomaviridae分类
医药卫生引用本文复制引用
谢珍,邢娟,石杨杨,吴昊,梅雅婷,吴大保..检测子宫上皮细胞游离亚铁原卟啉与人类乳头瘤病毒在宫颈癌筛查中的价值[J].中国临床保健杂志,2018,21(2):168-171,4.基金项目
吴阶平基金资助项目(320.6750.15123) （320.6750.15123）
