中国临床保健杂志2018，Vol.21Issue(2)：210-213,4.DOI:10.3969/J.issn.1672-6790.2018.02.019
健脾化湿清热通络药对活动期强直性脊柱炎患者血小板参数影响的数据挖掘
The data mining research of the Spleen and Clearing-heat Know Luo with Medicine for the platelet parameters effect of activity period ankylosing spondylitis patients
摘要
Abstract
Objective To applicate the association rules and statistical methods to analyze its applied spleen wet heat li rheumatism lead of t2dm with medicine treatment activity in patients with ankylosing spondylitis platelet pa -rameters and inflammation index,the influence of the immune index,in order to provide the basis for optimization of clin-ical drug use.Methods To sort out the first affiliated hospital of anhui medical university electronic medical records system data entry of ankylosing spondylitis patients.Using SPSS 21.0 software and SPSS 11.1 software clementine to an-alyse laboratory indexes before and after treatment and the traditional Chinese medicine association rule analysis and clustering analysis.Results (1)The treatment of ankylosing spondylitis li rheumatism lead of the commonly used drugs is divided into four categories:spleen lishi medicine medicine,promoting blood circulation to remove blood stasis drugs, functions of dehumidification,heat of poison.(2)Spleen wet heat t2dm medicine after active treatment of ankylosing spondylitis,patients with platelet parameters and inflammation,immune index were improved.(3)Traditional Chinese medicine and laboratory index correlation analysis found,caulis spatholobi,dried tangerine or orange peel,common club-moss herb,glandularstalk st.paulswortherb/common st.paulswort grass,spreading hedyotis herb,dandelion,radix scutel-lariae and platelet parameters related to the common clubmoss herb&dandelion is associated with the PLT.(4)When the Euclidean distance of 20,drugs can be divided into three broad categories.Class 1:peach kernel,safflower,red sage root,dried tangerine or orange peel,coix seed,clematis root,tuckahoe,yam,dandelion,spreading hedyotis herb,alisma,glandularstalk st.paulswortherb/common st.paulswort grass 12 herbs.Class 2:living alone,common clubmoss herb, caulis spatholobi 3 herbs.Class 3:including cortex phellodendri,rhizoma anemarrhenae,radix scutellariae,mulberry par-asitism,rhizoma ligustici wallichii 5 herbs.Conclusion Spleen,wet heat t2dm medicine can improve activity platelet parameters of patients with ankylosing spondylitis,reduce inflammatory indexes and adjust the immune indexes of pa-tients.关键词
脊柱炎,强直性/中草药/健脾/化湿/血小板计数/数据挖掘Key words
Spondylitis,ankylosing/Drugs/Chinese herbal/Strengthening spleen/Dissipating dampness/Platelet count/Data mining分类
医药卫生引用本文复制引用
方妍妍,刘健,万磊,忻凌,董文哲,文建庭,宋倩,黄旦..健脾化湿清热通络药对活动期强直性脊柱炎患者血小板参数影响的数据挖掘[J].中国临床保健杂志,2018,21(2):210-213,4.基金项目
安徽省科技攻关项目(1604a0802085) （1604a0802085）
中央引导地方科技发展专项(财教〔2016〕1188) （财教〔2016〕1188）
现代中医内科应用基础与开发研究安徽省重点实验室(财教〔2016〕518) （财教〔2016〕518）
2015年技术创新服务体系专项(财教〔2015〕1551) （财教〔2015〕1551）
中医药行业科研专项(201307001) （201307001）
