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慢性阻塞性肺疾病急性加重期伴肺栓塞的危险因素及临床特征

武红莉 田瑞雪 叶青 曹霞 宋育佳

中国临床保健杂志2018,Vol.21Issue(2):251-254,4.
中国临床保健杂志2018,Vol.21Issue(2):251-254,4.DOI:10.3969/J.issn.1672-6790.2018.02.029

慢性阻塞性肺疾病急性加重期伴肺栓塞的危险因素及临床特征

Risk factors and clinical characteristics analysis of acute exacerbation of chronic obstructive pulmonary disease with pulmonary embolism

武红莉 1田瑞雪 1叶青 1曹霞 1宋育佳1

作者信息

  • 1. 北京市海淀医院呼吸科,100080
  • 折叠

摘要

Abstract

Objective To study the risk factors and clinical characteristics of acute obstructive pulmonary dis -ease with pulmonary obstruction.Methods A retrospective analysis of pulmonary angiography confirmed acute exacer-bation of chronic obstructive pulmonary disease in 126 patients,56 cases with pulmonary embolism as the observation group,the remaining 70 cases as the control group,to analyse the clinical characteristics of the two groups of patients by univariate analysis and logistic multivariate regression analysis.Results The incidence of syncope was significantly higher in the observation group than that in the control group(23.2% VS.2.9%).The asymmetry of lower extremity was ≥1 cm(46.4%),deep venous thrombosis of lower extremity(53.6%),bedtime≥7d(66.1%),history of histo-ry and history of fracture(23.2%)and history of venous thrombosis(39.3%)were significantly higher than those in non-pulmonary embolism group(12.9%,12.9%,38.6%,5.2%and 11.4%,P<0.05).The level of SPAP,D-dimer and PaCO2in the observation group was significantly higher than that in the control group(P<0.05),and the incidence of SIQⅢTⅢsyndrome and ST-segment were significantly higher in the observation group than in the control group,The difference between the two groups was significant(P<0.05).Logistic multivariate regression analysis showed that inci-dence of syncope and venous thrombosis were independent risk factors for COPD emergency episodes with pulmonary embolism.Conclusion The patients with acute exacerbation of COPD had ≥7d bedtime,deep venous thrombosis and asymmetric swelling of both lower extremities ≥1cm and venous thrombosis are associated with high risk factors associ-ated with pulmonary embolism.When the symptoms aggravated with syncope,SIQⅢTⅢs and high SPAP,D-dimer and PaCO2levels,the patients should be alert to pulmonary embolism.

关键词

慢性阻塞性肺疾病急性加重期/肺栓塞/危险因素/临床特征

Key words

Acute obstructive pulmonary disease Acute exacerbation/Pulmonary embolism/Risk factors/Clini-cal features

分类

医药卫生

引用本文复制引用

武红莉,田瑞雪,叶青,曹霞,宋育佳..慢性阻塞性肺疾病急性加重期伴肺栓塞的危险因素及临床特征[J].中国临床保健杂志,2018,21(2):251-254,4.

中国临床保健杂志

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1672-6790

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