日用化学工业2018，Vol.48Issue(2)：99-102,4.DOI:10.13218/j.cnki.csdc.2018.02.008
蛇皮胶原蛋白的提取工艺及优化
Snake skin collagen extraction process and its optimization
丁瑞敏 1周华锋 2李赟高 2蔡衡 3段明星 3靳清贤3
作者信息
- 1. 郑州轻工业学院材料与化学工程学院,河南郑州450001
- 2. 清华大学生命科学学院,北京100084
- 3. 江苏隆力奇生物科技股份有限公司,江苏 常熟215500
- 折叠
摘要
Abstract
Taking snake skin as raw material,and the extraction rate of collagen as the index,the high temperature acid method was used to extract collagen.The influencesof the organic acid types and the concentration of citric acid,extraction temperature,extraction time and solid-to-liquid ratio on the extraction rate of collagen were studied.Based on single factor experiment,the extraction process of collagen of snake skin was optimized by orthogonal test.The optimized extraction process was obtained by acid extraction method which is found at the conditions of 1 mol/L initial concentration of citric acid as extraction agent with the solid-to-liquid ratio of 1∶60 (g∶ mL),at a temperature of 110 ℃ of 3 h,the extraction rate is 87.01％.关键词
化妆品原料/蛇皮/胶原蛋白/提取/柠檬酸Key words
cosmetic ingredient/snake skin/collagen/extraction/citric acid分类
化学化工引用本文复制引用
丁瑞敏,周华锋,李赟高,蔡衡,段明星,靳清贤..蛇皮胶原蛋白的提取工艺及优化[J].日用化学工业,2018,48(2):99-102,4.
