现代检验医学杂志2018，Vol.33Issue(1)：112-114,3.DOI:10.3969/j.issn.1671-7414.2018.01.028
免疫性血小板减少患者外周血Treg及Th1,Th2细胞检测及其临床意义
Detection and Clinical Significance of Treg and Th1,Th2 Cells in Peripheral Blood of Patients with Immune Thrombocytopenia
摘要
Abstract
Objective To detect the level of CD4+CD25+FoxP3+ (Treg) and Th1,Th2 cells in peripheral blood of patients with immune thrombocytopenia and discuss its clinical significance.Methods Flow cytometry was used to detect the percentage of Treg cells and Th1,Th2 cells in peripheral blood of 27 patients with ITP.25 healthy volunteers were detected as control group.Results The percentage of Treg cells in the peripheral blood of patients with ITP was (2.20 ± 0.93)％,which significantly decreased compared with the healthy control group (2.99 ± 0.45) ％ (t =3.820,P＜0.01) respectively,and the levels of Th1,Th2 cells were not statistically different between the two groups (tTh1 =0.655,tTh2 =0.467,all P＞ 0.05).Conclusion Treg cells in patients with ITP were decreased,and its important role in the development of ITP deserves further study.关键词
免疫性血小板减少/Treg/Th1/Th2Key words
immune thrombocytopenia/treg/Th1/Th2分类
医药卫生引用本文复制引用
高硕,徐学静,王森,程莉,陈军浩,孙健..免疫性血小板减少患者外周血Treg及Th1,Th2细胞检测及其临床意义[J].现代检验医学杂志,2018,33(1):112-114,3.基金项目
南京市医学科技发展资金(YKK15138). （YKK15138）
