特产研究2018，Vol.40Issue(1)：26-31,6.DOI:10.16720/j.cnki.tcyj.2018.01.007
ICP-MS法测定白花蛇舌草与水线草中的人体必需微量元素
Determination of Trace Elements in Hedyotis diffusa Willd.and Hedyotis corymbosa (L.) Lam.by ICP-MS
王亚茹 1李雅萌 1周柏松 1杨娜 1郑炳真 1李平亚 1刘金平1
作者信息
- 1. 吉林大学药学院天然药物研究中心,长春130021
- 折叠
摘要
Abstract
The aim is to further distinguish two kinds of anti-cancer Chinese herbal medicine with the determination of essential trace elements in Hedyotis diffusa Willd.and its adulterant Hedyotis corymbosa (L.) Lam.The fine powder of two herbs were treated with the method of electric heating digestion,and the Inductively Coupled Plasma Mass Spectrometry (ICP-MS) was used to determine 14 kinds of essential trace elements of human,such as Mn,Cr,Sr,Zn,Rb,B,Ni,Cu,V,Sn,As,Mo,Se,Co.The methodological study result showed that the linear relationship of these 14 elements was all good enough in the range of 0μg/g-500 μg/g,and the linear correlation coefficients (r) were all greater than 0.999 8.The detection limits were in the range of 0.001 9μg/g-0.164 4μμg/g,and the recoveries were between 97.5％ and 120.0％.The measurement results showed that the contents of other 13 elements in H.corymbosa (L.) Lam.were greater than in H.diffusa Willd.except Sn.What's more,the contents of Mn、Cr、Sr、Zn were relatively high in both two kinds of herbs.The established method of ICP-MS was validated with good linearity,sensitivity and accuracy.In these two herbs,the contents of 14 kinds of essential trace elements of human were different significantly,and this study could provide data support and reference for clarifying the different pharmacodyamic material basis for these two anti-cancer herbs.关键词
白花蛇舌草/水线草/电感耦合等离子体质谱法/人体必需微量元素Key words
Hedyotis diffusa Willd./Hedyotis corymbosa (L.) Lam./ICP-MS/essential trace elements分类
医药卫生引用本文复制引用
王亚茹,李雅萌,周柏松,杨娜,郑炳真,李平亚,刘金平..ICP-MS法测定白花蛇舌草与水线草中的人体必需微量元素[J].特产研究,2018,40(1):26-31,6.
