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临床样本中水貂嵌杯病毒的全基因组分析

王楷宬 庄青叶 邱源 王素春 侯广宇

畜牧兽医学报2018,Vol.49Issue(4):771-776,6.
畜牧兽医学报2018,Vol.49Issue(4):771-776,6.DOI:10.11843/j.issn.0366-6964.2018.04.014

临床样本中水貂嵌杯病毒的全基因组分析

Genome Analysis of the Mink Calicivirus Detected in Clinical Sample

王楷宬 1庄青叶 1邱源 1王素春 1侯广宇1

作者信息

  • 1. 中国动物卫生与流行病学中心,青岛266032
  • 折叠

摘要

Abstract

To analyze the characterization of the mink calicivirus in China,the genome of the mink calicivirus detected in the farm of Qingdao was sequenced by high-throughput sequencing.The genome of the isolate was analyzed and compared with other caliciviruses.The results showed that the length of the isolate was 8 427 bp,which possessed the similar genomic organization,structure and gene order with the other calicivirus.It possessed 5'-untranslated region and 3'-poly(A) tail.The comparing analysis of the genome and capsid protein amino acid sequence of the virus and the 19 representative viruses showed that the identity between this virus and the Chinese virus detected in 2011 was high.The BLAST results showed that this virus was not belong to mink enteric calicivirus.The analysis was also useful to supply reference to the classification of the caliciviruses which haven't been defied into genera.

关键词

水貂嵌杯病毒/基因组/分析/高通量测序

Key words

mink calicivirus/genome/analysis/high-throughput sequencing

分类

农业科技

引用本文复制引用

王楷宬,庄青叶,邱源,王素春,侯广宇..临床样本中水貂嵌杯病毒的全基因组分析[J].畜牧兽医学报,2018,49(4):771-776,6.

基金项目

国家重点研发计划项目(2017YFC120050) (2017YFC120050)

中国动物卫生与流行病学中心创新基金(2015IF-0004FF) (2015IF-0004FF)

畜牧兽医学报

OA北大核心CSCDCSTPCD

0366-6964

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