中国临床医学2018，Vol.25Issue(2)：178-181,4.DOI:10.12025/j.issn.1008-6358.2018.20180344
全球首例经口内镜肌切开术治疗贲门失弛缓症合并先天性成骨不全的临床实践
Peroral endoscopic myotomy for achalasia of cardia complicated with congenital osteogenesis imperfecta:the first clinical practice in the worldwide
摘要
Abstract
Objective:To solve the symptoms of achalasia complicated with osteogensis imperfecta through peroral endoscopic myotomy(POEM).Methods: The 21-year-old male patient,being diagnosed as achalasia complicated with osteogensis imperfecta,underwent POEM under general anesthesia after preoperative assessment of achalasia(Eckardt score of 7).The mucosal incision was made at a distance of 28 cm from the incisor,then the gastroscope entered the submucosal layer and tunnel in it,and myotomy was performed about 29 cm from the incisor extending 2 cm into the cardia.Electrocoagulation was performed to stop bleeding and the mucosal incision was then closed.Results:The operation was completed successfully in about 28 minutes.The stomach tube was removed 30 h after surgery.The patient was discharged in a stable condition on the fourth postoperative day.The follow-up result showed no recurrence in symptom with Eckardt score of 0 two weeks after operation.Conclusions:POEM is a feasible and effective way for achalasia of cardia complicated with osteogenesis imperfecta.关键词
经口内镜肌切开术/贲门失弛缓症/先天性成骨不全Key words
peroral endoscopic myotomy/achalasia of cardia/osteogenesiimperfecta分类
医药卫生引用本文复制引用
诸炎,李全林,蔡明琰,胡健卫,钟芸诗,蔡世伦,陈巍峰,张轶群,周平红..全球首例经口内镜肌切开术治疗贲门失弛缓症合并先天性成骨不全的临床实践[J].中国临床医学,2018,25(2):178-181,4.基金项目
国家自然科学基金(81301760,81470811,81670483),上海市科委重大项目(16411950400).Supported by National Natural Science Foundation of China(81301760,81470811,81670483)and the Major Project of Shanghai Municipal Science and Technology Committee(16411950400). （81301760,81470811,81670483）
