中国临床医学2018，Vol.25Issue(2)：182-187,6.DOI:10.12025/j.issn.1008-6358.2018.20180002
基于单中心的局部巨大乳腺癌手术切除后胸壁重建及巨大创面修复策略
Optimization strategies for thoracic wall reconstruction and repairing the huge soft-tissue defects after locally advanced breast cancer resection based on 11 years clinical experiences in a single Chinese center
朱明 1马晓飞 2杨燕文 1张勇 1冯自豪 1亓发芝 1顾建英1
作者信息
- 1. 复旦大学附属中山医院整形外科,上海 200032
- 2. 御颜医疗美容诊所,北京 100000
- 折叠
摘要
Abstract
Objective:To review and summarize our experience of surgical approach and reconstructive strategy for locally advanced breast cancer(LABC).Methods:A retrospective study was conducted using the medical records of 252 patients who underwent LABC treatment in our department from March 2006 to August 2017.Totally 197 of them were primary tumor and 55 were secondary.All the patients were received neoadjuvant chemotherapy.Surgical technology and clinical outcomes were compared and statistical analyzed.Results:The average hospital stay time of these patients was(12.9 ± 3.4)d(9-45 d),and the follow-up period after surgery was(18.7 ± 9.6)months(5-72 months).The size of tumor ranged 30 cm×25 cm to 5 cm×13 cm.71 of these cases had the whole chest wall defect,which 41 of them reconstructed with titanium mesh to establish the stability of chest.The sizes of flaps for reconstructing soft tissue defects ranged 14 cm×6 cm-29 cm×30 cm.Different flaps were selected for covering the chest wall defect,which local flaps for 16 case(6.3%);pectoralis major myocutaneous combined with breast flaps for 31 cases(12.3%);lateral thoracic flaps for 34 cases(13.5%);latissimus dorsi myocutaneous flaps with pedicle for 98 cases(38.9%);rectus abdominis musculocutaneous flaps for 56 cases(22.2%)and deep inferior epigastric perforator flaps(DIEP flaps)for 17 cases(6.7%).All the patients recovered well,and the function and appearance of chest wall were satisfactory(P< 0.05).Conclusions:Plastic technology for reconstruction provides a useful strategy and method for LABC treatment,and is able to improve the life quality and prognosis of the patients.关键词
局部巨大乳腺癌/手术治疗/胸壁缺损/胸壁重建Key words
localladvancebreast cancer/surgical treatment/chest wall defect/chest wall reconstruction分类
医药卫生引用本文复制引用
朱明,马晓飞,杨燕文,张勇,冯自豪,亓发芝,顾建英..基于单中心的局部巨大乳腺癌手术切除后胸壁重建及巨大创面修复策略[J].中国临床医学,2018,25(2):182-187,6.
