中国临床医学2018，Vol.25Issue(2)：199-202,4.DOI:10.12025/j.issn.1008-6358.2018.20170946
基于单中心的原发性局限期食管小细胞癌根治手术临床疗效分析
The role of radical surgery in treatment of limited-stage primary small cell carcinoma of the esophagus based on clinical data of single center in China
摘要
Abstract
Objective:To investigate the clinical experience of radical surgery in treatment of limited-stage primary small cell carcinoma of the esophagus(PSCCE),and to optimize the treatment strategy of PSCCE.Methods: This retrospective study was designed to investigate the clinical characteristics of 30 PSCCE patients from October 1,2010 to July 31,2017 in Department of Thoracic Surgery,Changhai Hospital,Naval Military Medical University.The data of treatment and follow-up were analyzed in order to summarize the treatment experience.Results: The accuracy rate of preoperative gastroscopy pathological diagnosis was 13.33% (4/30),and 80% (24/30)was performed operation combined with chemotherapy.Three cases had postoperative complications,but all the patients were discharged successfully.The 1-,2-,and 3-year average overall survival rate of 30 patients were 54.8%,35.1%,and 26.4%,respectively.The multivariate analysis showed that lymph node metastasis was an independent prognostic factor for the patients with PSCCE.Conclusions:The choices of treatment for PSCCE remain uncertain,surgical resection combined with chemotherapy is effective for patients with PSCCE.The patients with lymph node metastasis may not benefit from radical surgery.关键词
食管肿瘤/癌,小细胞/外科手术/预后Key words
esophageal neoplasms/carcinoma/small cell/surgical procedures/operation/prognosis分类
医药卫生引用本文复制引用
徐志远,陆超敬,李春光,王晓伟,金海,杨立信,陈和忠,朱吉..基于单中心的原发性局限期食管小细胞癌根治手术临床疗效分析[J].中国临床医学,2018,25(2):199-202,4.基金项目
国家自然科学基金(81602161).Supported by National Natural Science Foundation of China(81602161). （81602161）
