中国现代医学杂志2018，Vol.28Issue(12)：12-16,5.DOI:10.3969/j.issn.1005-8982.2018.12.002
不同抗菌涂层对种植体周围炎骨吸收影响的动物研究
Animal experimental study on effect of different antibacterial coatings on absorption of peri-implant inflammation
王晓婧 1乔梦婷2
作者信息
- 1. 北京大学第三医院 口腔科,北京 100091
- 2. 中国医科大学航空总医院口腔修复科,北京 100012
- 折叠
摘要
Abstract
Objective To investigate the anti-inflammatory effect of different antibacterial material coated on dental implants in animal model of peri-implant inflammation. Methods A total of 30 titanium rods were randomly divided into 3 groups based on material coated on the rod surface: silver electrodeposition (Ti-Ag group), silanization treatment (Ti-Si group) and non-coated rods (control group). Six dental implants were inserted in the mandibular premolar sites of beagle dog (n = 5). Peri-implantitis was initiated by ligation at neck of the implant for 2 months. Identification of peri-implantitis was achieved by plaque index, modified sulcus bleeding index, probing depth, gingival index, mobility of implant, X-ray examination and histological analysis. Results Control group showed mucosa with severe edema (even ulcer or fester), dull percussion and implant loosening, which were significantly alleviated in both Ti-Ag and Ti-Si group. Clinical indexes mentioned above suggested that animals in Ti-Ag and Ti-Si group experienced better recovery when compared with control group. No obvious dramatic difference was founded between Ti-Ag group and Ti-Si group (P > 0.05). X-ray showed no obvious bone resorption around implants in both Ti-Ag and Ti-Si groups while dogs in control group showed obvious vertical absorption of alveolar bone around implant indicated by obvious transmission between bone and implants. Histological staining indicated significantly improved osseointegration in Ti-Ag and Ti-Si groups compared with control group (P < 0.05). Conclusion Antibacterial Ti-Ag and Ti-Si coated rods reduce local inflammation and bone resorption in peri-implantitis.关键词
抗菌涂层/钛种植体/种植体周围炎/骨吸收Key words
antibacterial coating/titanium implant/peri-implantitis/bone resorption分类
医药卫生引用本文复制引用
王晓婧,乔梦婷..不同抗菌涂层对种植体周围炎骨吸收影响的动物研究[J].中国现代医学杂志,2018,28(12):12-16,5.
