中国现代医学杂志2018，Vol.28Issue(12)：97-100,4.DOI:10.3969/j.issn.1005-8982.2018.12.017
高危HPV阴性宫颈癌患者的临床病理特征研究
Clinicopathological characteristics of high-risk human papillomavirus negative cervical cancer
陈倩 1方绳权1
作者信息
- 1. 湖北省肿瘤医院 妇瘤科,湖北 武汉 430079
- 折叠
摘要
Abstract
Objective To investigate the clinicopathological features of high-risk human papillomavirus (HPV) negative cervical cancer. Methods Retrospective analysis of the clinical data of 1123 cases of cervical cancer in our hospital from January 2013 to January 2017 was made, all the patients were diagnosed with cervical cancer by HPV-DNA test and thin-layer liquid-based cytology. There are 13 types of high-risk HPV positivity.Age, clinical stage and pathological type of the patients were analyzed and the screening value of HPV-DNA test and TLC-based cytology test were compared. Results There was no significant difference in the age of high-risk HPV-positive group and high-risk HPV negative group (P > 0.05). The proportion of adenocarcinoma in high-risk HPV-negative group was higher than that in high-risk HPV group (P < 0.05). Diagnostic sensitivity and negative predictive value were higher in high-risk HPV-negative cervical cancer with HPV-DNA detection. Conclusion HPV-DNA can be used for diagnosis of high-risk HPV negative cervical cancer; onset age of the cancer is from 36 years old to 50 years old and adenocarcinoma dominates.关键词
高危/人乳头瘤病毒/宫颈癌/临床病理特征Key words
high risk/human papillomavirus/cervical cancer/clinicopathological characteristics分类
医药卫生引用本文复制引用
陈倩,方绳权..高危HPV阴性宫颈癌患者的临床病理特征研究[J].中国现代医学杂志,2018,28(12):97-100,4.
