中国药理学通报2018,Vol.34Issue(5):597-600,4.DOI:10.3969/j.issn.1001-1978.2018.05.002
炎性环境与间充质干细胞自噬相互影响关系的研究进展
The research progress of interaction between inflammatory environment and MSCs autophagy
摘要
Abstract
Mesenchymal stem cells (MSCs) can participate in the repair of various tissue and organ damage, but inflammation often exists in local repair area,and autophagy is induced. As a kind of self-regulating mechanism of cells, autophagy can not only regulate the physiological process of MSCs under inflamma-tory environment, but also work on anti-inflammatory environ-ment. This research focuses on the relations between inflamma-tory environment and MSCs autophagy's interaction and feed-back regulation, providing a train of thought for research of MSCs in inflammatory environment.关键词
炎性环境/炎性因子/自噬/间充质干细胞/反馈调节/病原相关分子模式Key words
inflammatory environment/inflammatory cytokines/autophagy/mesenchymal stem cells/feedback regulation/pathogen-associated molecular patterns分类
医药卫生引用本文复制引用
李程豪,刘永琦,骆亚莉,伍志伟..炎性环境与间充质干细胞自噬相互影响关系的研究进展[J].中国药理学通报,2018,34(5):597-600,4.基金项目
国家自然科学基金资助项目(No 81360588,8176084) (No 81360588,8176084)