重庆医学2018，Vol.47Issue(12)：1595-1598,4.DOI:10.3969/j.issn.1671-8348.2018.12.008
死腔分数对急性呼吸窘迫综合征预后的评估价值
Evaluation value of dead-space fraction on prognosis of acute respiratory distress syndrome
摘要
Abstract
Objective To investigate the dynamic changes of dead space fraction (VD/VT) and its effect on the prognosis in the patients with acute respiratory distress syndrome (ARDS).Methods Thirtytwo patients with ARDS in EICU of the First Affiliated Hospital of Kunming Medical University from January 2015 to August 2016 were selected and divided into the survival group and the death group according to the 28 d mortality rate.VD/VT on 1-6 d in the two groups was calculated according to the formula.The parameters of basic condition,PaO2/FiO2,APACHE Ⅱ score,LIPS score,PEEP of the two groups were compared.Results LIPS and APACHE Ⅱ scores had statistical difference between the death group and survival group (P＜0.05);VD/VT on 1-3 d had no statistical difference between the two groups (P＞0.05),and VD/VT on 4-6 d in the death group was significantly higher than that in the survival group (P＜0.01).△PCO2,pH and PaO2/FiO2 had statistical difference between the death group and the survival group (P＜0.05).The binary classification Logistic regression analysis found that APACHE Ⅱ,LIPS,△PCO2,VD/VT were the risk factors.VD/VT on the 4th day was selected,its' cut off value was 0.62,and the sensitivity of the prognostic evaluation was 90.0 ％,the specificity was 95.5 ％.Conclusion The dead space fraction is an independent risk factor for the prognosis of ARDS patients,and VD/VT on 4th day could effectively identify the high-risk patients.关键词
呼吸窘迫综合征,成人/肺/死腔分数/急性呼吸窘迫综合征/机械通气/预后Key words
respiratory distress syndrome, adult/lung/dead space fraction/acute respiratory distress syndrome/mechanical ventilation/prognosis分类
医药卫生引用本文复制引用
徐冕,杨德兴,颜悦新,刘桠名,周凤高,许成,刘荣..死腔分数对急性呼吸窘迫综合征预后的评估价值[J].重庆医学,2018,47(12):1595-1598,4.基金项目
云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(2014FZ007). （2014FZ007）
