国际口腔医学杂志2018，Vol.45Issue(3)：261-266,6.DOI:10.7518/gjkq.2018.03.003
牙髓干细胞的表观遗传调控
Epigenetic regulation in dental pulp stem cells
摘要
Abstract
Dental pulp stem cells (DPSCs) are adult stem cells with self-renewal ability and multiple differentiation potential. These cells play an important role in dental pulp repair, tooth regeneration, and bone tissue engineering. Epigenetics refers to heritable changes in gene expression without alteration of DNA sequence; these changes include DNA methylation, histone modification, and non-coding RNA regulation. Epigenetic modification plays an important role in regulation of DPSCs by influencing gene transcription. Thus, this study aims to elaborate epigenetic regulations of DPSCs.关键词
表观遗传/牙髓干细胞/DNA甲基化/组蛋白修饰/非编码RNAKey words
epigenetic/dental pulp stem cell/DNA methylation/histone modification/non-coding RNA分类
生物科学引用本文复制引用
张鑫,汪成林,杨静,叶玲..牙髓干细胞的表观遗传调控[J].国际口腔医学杂志,2018,45(3):261-266,6.基金项目
国家国际科技合作专项项目(2014DFA31990)This study supported by International Science&Technology Cooperation Program of China(2014DFA31990). （2014DFA31990）
