国际口腔医学杂志2018，Vol.45Issue(3)：267-271,5.DOI:10.7518/gjkq.2018.03.004
长链非编码RNA在间充质干细胞多向分化过程中的调节作用
Regulate process of long non-coding RNA in multi-differentiation of mesenchymal stem cells
摘要
Abstract
Mesenchymal stem cells (MSCs) derived from mesoderm exhibit self-renewal and multiple differentiation potentials. MSCs are considerably useful in tissue repair and cell development, with the ability to differentiate into osteoblasts, chondrocytes, adipocytes, myoblasts, neurocytes and other cells. Long noncoding RNAs (lncRNAs) are differentially expressed in the differentiation of MSCs. This result indicated that lncRNAs are crucial in regulation during differentiation. To date, most reports mainly focused on microarray and bioinformatics analysis of lncRNAs. The function and regulatory mechanism of lncRNAs on the differentiation of MSCs still remain unclear. However, with the development in new research technologies, the regulatory mechanism of lncRNA in the differentiation of MSCs will be intensively elucidated.关键词
间充质干细胞/长链非编码RNA/多向分化Key words
mesenchymal stem cell/long noncoding RNA/multi-differentiation分类
生物科学引用本文复制引用
葛逸弘,房付春,吴补领..长链非编码RNA在间充质干细胞多向分化过程中的调节作用[J].国际口腔医学杂志,2018,45(3):267-271,5.基金项目
国家自然科学基金(81600882) （81600882）
广东省医学科学技术研究基金(A2016190)This study was supported by National Natural Science Fundation of China(81600882)and Medical Scientific Research Foundation of Guangdong Province(A2016190). （A2016190）
