广西科学2018，Vol.25Issue(1)：26-31,35,7.DOI:10.13656/j.cnki.gxkx.20180206.003
水生生物病原核酸适配体研究进展
Advances in Study of Aptamers in Pathogens of Aquatic Organisms
摘要
Abstract
Aptamers generated by selective evolution of ligands by exponential enrichment (SELEX) are short,single-stranded nucleic acid oligomers.They display a high degree of affinity and specificity for their targets,and widely used in rapid detection and targeted therapy study.In recent years,frequent outbreaks of aquatic bacterial and viral pathogenic diseases have severely restricted the health of aquatic ecosystems and the rapid development of aquaculture.As a new type of recognition molecule,aptamers have been applied in related study and acquired some achievements.In this paper,the selection of aquatic bacterial and viral pathogen aptamers and their research status in the field of detection and treatment are reviewed,and the application prospects of aptamers in this field are prospected.关键词
SELEX/核酸适配体/水生生物细菌/病毒性病原/快速检测Key words
SELEX/aptamer/aquatic bacteria/viral pathogenic/aquatic分类
农业科技引用本文复制引用
周伶俐,李鹏飞,秦启伟..水生生物病原核酸适配体研究进展[J].广西科学,2018,25(1):26-31,35,7.基金项目
国家自然科学基金项目(41706145),广西自然科学基金项目(2017GXNSFBA198176)和广西科学院基本科研业务费项目(2017YJJ23002)资助. （41706145）
