湖南中医药大学学报2018，Vol.38Issue(4)：430-434,5.DOI:10.3969/j.issn.1674-070X.2018.04.017
基于数据挖掘的许华教授治疗过敏性紫癜用药规律探讨
Medication Regularity of XU Hua in Treating Allergic Purpura Based on Data Mining
摘要
Abstract
Objective Based on data mining technology, medication rules of Professor XU Hua in treatment of allergic purpura were investigated, to provide quantitative data support for better inheriting her academic experience. Methods The cases of professor XU Hua in treatment of allergic purpura were collected, data was put into TCM inheritance support system to build database. The principle analysis, improved mutual information method, complex system entropy clustering, topology of network and other data mining methods were used for statistical analysis. Results The 164 medical records and 233 prescriptions were analyzed, and the main symptoms and combination rules of core herbs were extracted. The results showed that the symptoms of the first 6 were lung (-), diaphane, naoko, liverwort, pharynx(-), and pharynx(+). The core of the frequency of the top 10 drugs have purple perilla leaf (Zisuye), red paeony root (Chishao), periostracum cicada (Chantui), windproof (Fangfeng), radix arnebiae seu lithospermi (Zicao), radix rehmanniae (Shengdihuang), cortex moutan (Mudanpi), white cardamom (Baidoukou), madder (Qiancao), forsythia (Lianqiao), cogongrass rhizome (Baimaogen). The main functions of the medicines were r educing the wind to nourish, heat-clearing and detoxifying, cooling blood to remove stasis. Three new prescriptions were also derived, which mainly focused on the symptoms of rashes and kidney damage. Conclusion The medicines of clearing heat and cooling blood (Qingre Liangxue), dispelling wind and expelling blood stasis (Qufeng Huayu) were commonly used by Professor XU Hua in treating allergic purpura. It is often accompanied by the herbs of regulating Qi and transforming dampness, which reflects the dialectical thought of "the pathogenesis of allergic purpura associated with exogenous pathogenic factors" and the experience of "mainly using the method of eliminatin".关键词
过敏性紫癜/用药规律/数据挖掘/中医传承辅助平台/许华Key words
allergic purpura/medication regularity/data mining/traditional Chinese medicine inheritance support system/XU Hua分类
医药卫生引用本文复制引用
刘华,陈子茵,许华,陈国铭,綦向军,梁妙珍,陈腾宇,张洁,田燕华,冯惜怡,张琳琳..基于数据挖掘的许华教授治疗过敏性紫癜用药规律探讨[J].湖南中医药大学学报,2018,38(4):430-434,5.基金项目
广州中医药大学中医学术流派传承项目:岭南黎氏儿科学术流派(2015LP03). （2015LP03）
