湖南中医药大学学报2018，Vol.38Issue(4)：455-458,4.DOI:10.3969/j.issn.1674-070X.2018.04.023
香砂六君子汤对乳腺癌化疗患者的减毒及增效作用观察
Synergy and Attenuation Effects of Xiangsha Liujunzi Decoction on Breast Cancer Patients with Chemotherapy
摘要
Abstract
Objective To observe the synergy and attenuation effect of Xiangsha Liujunzi decoction on cancer patients with chemotherapy. Methods A total of 120 cases of breast cancer patients were randomly divided into observation group and control group according to random number table, 60 cases in each group. The two groups were given cyclophosphamide combined with epirubicin 4 cycle sequential docetaxel 4 cycle (EC×4-T×4) scheme preoperatively. The observation group was given Xiangsha Liujunzi decoction on the basis of the control group. The toxic and side effects of the two groups, such as clinical benefit rate (CBR), nausea and vomiting, hair loss, diarrhea, reduced white blood cell count, elevated levels of alanine aminotransferase, were compared, and the quality of life before and after treatment was also compared between the two groups. Results The CBR of the observation group was 96.67%, which was significantly higher than 86.67% in control group (P<0.05). The grading of nausea and vomiting, reduced white blood cell count in the observation group was significantly lighter than those in control group (P<0.05). After treatment, the physiological status, emotional status, FACT-G total score and FACT-B score of the observation group were significantly higher than those of the control group (P<0.05). Conclusion Xiangsha Liujunzi decoction could significantly enhance the efficacy and reduce toxicity, worthy of promoting.关键词
乳腺癌/化疗/香砂六君子汤/减毒/增效/临床观察Key words
breast cancer/chemotherapy/Xiangsha Liujunzi decoction/attenuation/synergy/clinical observation分类
医药卫生引用本文复制引用
刘丹,谢枫枫,陈莹..香砂六君子汤对乳腺癌化疗患者的减毒及增效作用观察[J].湖南中医药大学学报,2018,38(4):455-458,4.基金项目
广东省医药管理局项目(201611922331972). （201611922331972）
