周亚雄 1刘海鹏 2祝占奎 2何晓娜 3任弟娟 1陈晓2
作者信息
- 1. 兰州大学第二临床医学院,甘肃兰州 730030
- 2. 兰州大学第二医院甘肃省消化系肿瘤重点实验室,甘肃兰州 730030
- 3. 兰州大学第二医院普外三科,甘肃兰州 730030
- 折叠
摘要
Abstract
Objective To clarify the clinical effectiveness of placing drainage and no-drainage after thyroid and parathyroid surgery.Methods The databases were retrieved orderly from the dates of their establishment to November 29th,2016,including PubMed,EMbase,The Cochrane Library and so on.The literature was screened strictly according to inclusive criteria.After the study selection,assessment and data extraction were conducted by the two reviewers independently,and Meta-analyses were performed by using RevMan5.3 soft ware.The level of evidence was assessed by using the GRADEpro3.6 soft ware.Results A total of 23 studies involving 3 036 participants were included.There was no significant difference between the two groups in the rate of re-operation,hematoma,sermon,hemorrhage and the slight bulge in the neck that does not need to deal with.However,the wound infection rates were significantly different between the two groups [RR =2.51,95% CI (1.28 to 4.92),I2=0%,P=0.008];as were Incision pain score for the intraday after operation [SMD =0.70,95% CI (0.26 to 1.14),I2 =76%,P=-0.002],and the first day after operation [SMD=1.26,95% CI (0.75 to 1.77),I2=93%,P<0.000 1];and the length of hospital stay also was significantly different [SMD=1.74,95% CI(1.27 to 2.21),I2 =96%,P<0.000 01].Conclusion The evidence showed that routine drainage after thyroid and parathyroid surgery can not significantly reduce the incidence of postoperative complications;instead,they can increase the rates of wound infection,the incision pain score and the duration of hospital stay.关键词
甲状腺/甲状旁腺/引流/Meta分析Key words
thyroid/parathyroid/drain/Meta-analysis分类
医药卫生