摘要
Abstract
Objective To investigate the influence of timing of percutaneous kyphoplasty(PKP) on curative effect in the treatment of patients with osteoporotic thoracolumbar vertebral compression fractures. Methods The 183 cases with osteoporotic thoracolumbar vertebral compression fractures were divided into 3 groups according to the time from injury to operation. The surgery time after injury of group A was within 1 week(112 cases),group B was within 1~3 weeks (53 cases),group C was >3 weeks (18 cases). The bone cement injection volume and leakage incidence rate during operation were compared among the three groups. The VAS and VAS improvement rate,changes of Cobb angle,improvement rate of anterior vertebral height were compared among the three groups. The life quality at 12 months after surgery was assessed by using the SF-36 Health Survey Scale. Results The bone cement injection vol-ume:the group A was higher than the group B and C(P<0.01),and the group B was higher than the group C(P<0.01). The leakage incidence rate of bone cement:the group A was higher than the group B and C(P<0.05), and the group B was higher than the group C(P<0.05). At 12 months postoperation,the VAS of three groups were significantly lower than the preoperative(P<0.01), and VAS of three groups had no differences(P>0.05); the group A had the higher improvement rate of VAS than group B and C(P<0.01),and no significant difference was found between group B and C (P>0.05). The Cobb angle at 12 months after operation was significantly lower than that in the three groups before operation(P<0.01),and there was no significant difference among the three groups (P>0.05);the improvement rate of the anterior vertebral body height in the group A was the highest,group C was the lowest,and there were significant differences between every two groups in the three groups (P<0.01). At 12 months postoperatively,the life quality scores showed that there were significant differences in 8 dimensions scores between group A and B(P<0.05,P<0.01),there were significant differences between group B and C in other di-mensions scores(P<0.01) except PF and RE dimensions,and there were significant differences in other dimensions scores between group A and C(P<0.05,P<0.01) except RP dimension. Conclusions The clinical effect of PKP within 1 week after injury in the treatment of patients with osteoporotic thoracolumbar vertebral compression fractures is significant.关键词
胸腰椎压缩骨折/经皮后凸成形术/骨质疏松Key words
thoracolumbar vertebral compression fractures/percutaneous kyphoplasty/osteoporosis分类
医药卫生
