临床神经病学杂志2018，Vol.31Issue(2)：89-92,4.
原发性中枢神经系统NK/T细胞淋巴瘤临床病理分析
Clinical pathological analysis of primary central nervous system extranodal natural killer/T-cell lymphoma
摘要
Abstract
Objective To explore the clinic-pathological features of primary central nervous system extranodal natural killer/T-cell lymphoma(PCNSL-NK/T).Methods The clinical data of one PCNSL-NK/T patient who treated in our hospital and other 12 PCNSL-NK/T patients from literatures were analyzed retrospectively.Results The median onset age of 13 PCNSL-NK/T patients in this study was 39 years, and the male to female ratio was 3.3:1.In this group,mainly were Asian patients(9 cases).Clinical and imaging findings were lack of specificity. The accurate diagnosis needed rely on the histomorphology,immunophenotype and molecular technique.The disease was highly aggressive, lack of effective treatment and with poor prognosis.In addition, one case of PCNSL-NK/T patient who treated in our hospital could expressed as CD 20.Conclusion The PCNSL-NK/T is extremely rare and highly aggressive,which may express the B cell marker CD 20.关键词
淋巴瘤/原发性中枢神经系统淋巴瘤/NK/T细胞淋巴瘤Key words
lymphoma/primary central nervous system lymphoma/natural killer/T-cell lymphoma分类
医药卫生引用本文复制引用
李杜娟,付芳芳,朱遂强,连立飞..原发性中枢神经系统NK/T细胞淋巴瘤临床病理分析[J].临床神经病学杂志,2018,31(2):89-92,4.基金项目
国家自然科学基金项目(81300215) （81300215）
河南省科技攻关计划项目(132102310095) （132102310095）
