临床神经病学杂志2018，Vol.31Issue(2)：99-102,4.
脑白质病变合并脑微出血相关危险因素研究
Research on relative risk factors of white matter lesions combined with cerebral microbleeds
摘要
Abstract
Objective To investigate relative risk factors of white matter lesions(WML)combined with cerebral microbleeds(CMB).Methods Ninety four patients with WML were diagnosed by MRI and susceptibility weighted imaging(SWI)and hospitalized in department of neurology of Huangshan city people's hospital from January 2014 to June 2017.The patients were divided into CMB group(59 cases)and non-CMB group(35 cases).The data of demographic,history of hypertension,diabetes, stroke, drinking and blood test results were classified, and then analyzed.Results The rates of smoking history and hypertension history, severity of WML and blood uric acid (UA)in CMB group were significantly higher than that of non-CMB group(all P<0.05).Single factors Logistic regression analysis showed that increase of blood UA, history of smoking and hypertension, severity of WML were closely related with CMB in the patients of WML(all P<0.05).Multiple factors Logistic regression analysis showed that the blood UA(OR=1.007,95%CI:1.002-1.012,P=0.009)and severity of WML(OR=1.584,95%CI:1.085-2.313, P=0.017)were independent risk factors for WML patients combined with CMB.Conclusion High UA and severe WML are independent risk factors for WML patients combined with CMB.关键词
脑白质病变/脑微出血/尿酸/危险因素Key words
white matter lesions/cerebral microbleeds/uric acid/risk factors分类
医药卫生引用本文复制引用
倪初源,程小华,曹毅,汪飞,吴晟昊,郭志浩,程蛰承..脑白质病变合并脑微出血相关危险因素研究[J].临床神经病学杂志,2018,31(2):99-102,4.基金项目
黄山市科技计划项目(2015Z-08) （2015Z-08）
