摘要
Abstract
Objective:To analyze the clinical efficacy of Hegan powder in the treatment of compensatory cir-rhosis and the effect of serum hyaluronic acid(HA),laminin(LN)and procollagen Ⅲ (PC III)expression level. Methods:84 cases of decompensated cirrhosis patients were as the research object,randomly divided into control group and study group,the control group was given lamivudine treatment,the study group was given at the same time the control group and the therapy with liver powder treatment,compared two groups of clinical curative effect evaluation after a course of treatment,observe the two groups before and after treatment in patients with HA,LN, PC Ⅲ changes in expression levels,statistics of the two groups during the treatment the incidence of adverse reac-tions to drug safety assessment.Results:The total effective rate of the control group was 88.10%,the total effec-tive rate of the study group was 95.24%,and that of the study group was higher than that of the control group(P<0.05).After treatment,the expression levels of serum HA,LN and PC Ⅲ were improved in the two groups com-pared with the level before treatment(P<0.05),the study group was more ideal than the control group(P<0. 05).The adverse reaction rate in control group was 14.29%,and the adverse reaction rate was 2.38% in study group,and that in study group was lower than that in control group(P<0.05).Conclusion:The Hegan powder can effectively improve the clinical efficacy of compensatory cirrhosis,and reduce the serum levels of HA,LN and PC Ⅲ expression.关键词
肝硬化/中西医结合疗法/透明质酸/层粘连蛋白/@和肝散Key words
Liver cirrhosis/integrated/Chinese traditional and western medicine therapy/Hyaluronic acid Laminin/@ Hegan powder分类
医药卫生
