陕西中医2018,Vol.39Issue(5):577-579,3.DOI:10.3969/j.issn.1000-7369.2018.05.010
醒脑通络汤联合高压氧对改善颅脑重度损伤患者意识功能障碍的作用研究
Xingnao Tongluo decoction combined with hyperbaric oxygen on the improvement of consciousness dysfunction in patients with severe craniocerebral injury
摘要
Abstract
Objective:To study the effect of Xingnao Tongluo decoction combined with hyperbaric oxygen therapy on conscious dysfunction in patients with severe craniocerebral injury.Methods:Severe injury patients as the research data of 74 cases were randomly divided into the control group and study group,the control group was given hyperbaric oxygen therapy,study group in the control group based on the therapy combined with Xingnao Tongluo decoction treatment,after a course of treatment,clinical evaluation the effect and comparative analysis,score statis-tics of two groups of patients awake time,prognosis of Glasgow(GOS),observed before and after treatment in two groups of serum myelin basic protein in patients with(MBP),neuron specific enolase(NSE)and S100 protein (S100-B)expression.Results:The total effective rate of the control group was 64.86%,the total effective rate of the study group was 78.38%,and the clinical efficacy of the study group was better than that of the control group(P<0.05).After treatment,the serum levels of MBP,NSE and S100-B in the study group were better than those in the control group,and the difference between the two groups was P<0.05.After treatment,the two groups im-proved compared with the treatment group,compared with P<0.05.The sober time of the patients in the study group was less than that of the control group,and the score of GOS was better than that of the control group(P<0. 05).Conclusion:Xingnao Tongluo decoction combined with hyperbaric oxygen therapy can effectively improve the severe traumatic brain injury patients with disturbance of consciousness,shorten the recovery time of patients,im-prove the prognosis of patients with quality,reduce serum markers expression of nerve injury.关键词
颅脑损伤/中西医结合疗法/@高压氧/@醒脑通络汤Key words
Craniocerebral trauma/integrated/Chinese traditional and western medicine therapy/@ Hy-perbaric oxygen/@ Xingnao Tongluo decoction分类
医药卫生引用本文复制引用
周汉光,张建党,张元峰,周祥..醒脑通络汤联合高压氧对改善颅脑重度损伤患者意识功能障碍的作用研究[J].陕西中医,2018,39(5):577-579,3.基金项目
河南省医学科技攻关计划项目(201203069) (201203069)