塑料科技2018，Vol.46Issue(4)：113-116,4.DOI:10.15925/j.cnki.issn1005-3360.2018.04.019
HPLC-MS/MS法测定聚碳酸酯食品包装材料中的酚类化合物
Determination of Phenolic Compounds in Polycarbonate Food Packaging Materials by HPLC-MS/MS
摘要
Abstract
A comprehensive analytical method based on liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) had been developed for the determination of 4 kinds of phenolic compounds in polycarbonate food packaging materials.The samples were extracted with dichloromethane under ultrasonication,and the extract was evaporated to dryness under nitrogen before constant-volumed with methanol.Finally,it was analyzed by HPLC-MS/MS.The ZORBAX Eclipse XDB C18 column and gradient elution were selected to separate with methanol-0.1％ (volume fraction) ammonia solution.The mass spectrometer was operated under multiple reaction monitoring (MRM) and ESI-mode.The results indicate that,the method shows good linear relationships for 4 phenolic compounds in the concentration range of 0.2～2 mg/L,with correlation coefficients above 0.999.The detection limits are in the range of 3～10 μg/kg,and the limits of quantitation are 10～50 μg/kg.The recoveries of 4 phenolic compounds are in the range of 84.4％～108.8％ at three spiked concentrations levels of 100,200 and 400 μg/L.The established method has the advantages of good separation,high accurancy,high recovery,convenience and rapidness.This will be lay a foundation for the risk monitoring of hazardous substances in food packaging materials.关键词
高效液相色谱-串联质谱法/聚碳酸酯/酚类化合物/食品包装材料Key words
HPLC-MS/MS/Polycarbonate/Phenolic compounds/Food packaging materials分类
化学化工引用本文复制引用
马洁清,丁枫芸,徐坚琪,吴晓芳,卢伦,马燕飞..HPLC-MS/MS法测定聚碳酸酯食品包装材料中的酚类化合物[J].塑料科技,2018,46(4):113-116,4.基金项目
浙江省质量技术监督系统科研计划项目(20170238) （20170238）
