实用肝脏病杂志2018，Vol.21Issue(3)：368-371,4.DOI:10.3969/j.issn.1672-5069.2018.03.013
加速康复外科在脾切除贲门周围血管离断术治疗门脉高压症患者临床应用研究
Clinical application of enhanced recovery after surgery program in patients with portal hypertention underwent pericardial devascularization with splenectomy
摘要
Abstract
Objective To investigate the clinical application of enhanced recovery after surgery(ERAS) program in patients with portal hypertention underwent pericardial devascularization with splenectomy. Methods Eighty patients with portal hypertension were recruited in our hospital in recent two years,and they were randomly divided into two groups. Forty patients underwent ERAS management during the perioperative period,and another forty patients underwent conventional perioperative treatment as control groups. Results The pain score 24 h and 48 h postoperation in the ERAS group were(2.1±0.6)and(2.2±0.6),much lower than(3.7±0.8)and(3.0±0.6) in the control(P<0.01);the postoperative anal exhaust time,extubation time and hospital stay in the ERAS group were(2.4±0.5)d,(5.2±0.8)d and(8.5±2.2)d,much shorter than(3.5±0.7)d,(7.6±3.0)d and(11.6±5.3)d in the control(P<0.01);serum alanine transaminase,total bilirubin and albumin levels 5 day after surgery were (27.6±11.3)U/L,(18.3±6.2)μmol/L and(41.8±5.4)g/L,while they were [(48.6±44.3)U/L,(23.3±11.5)μmol/l and(37.1 ±5.1)g/L,respectively,significantly different between the two groups(P<0.01);there were 19 cases (47.5%)having complications after operation in the ERAS group,much lower than 29 cases(72.5%)in the control group(P<0.05). Conclusion ERAS in the perioperative management of patients with portal hypertension is effective and safe,which might accelerate the recovery of patients.关键词
门脉高压症/加速康复外科/脾切除术,贲门周围血管离断术/康复Key words
Portal hypertension/Enhanced recovery after surgery/Splenectomy/Pericardial devascularization/Recovery引用本文复制引用
李亮亮,马金良,荚卫东,张传海,韩梅,李国芹..加速康复外科在脾切除贲门周围血管离断术治疗门脉高压症患者临床应用研究[J].实用肝脏病杂志,2018,21(3):368-371,4.基金项目
安徽省自然科学基金资助项目(编号:1608085MH 198) （编号:1608085MH 198）
