实用肝脏病杂志2018,Vol.21Issue(3):372-375,4.DOI:10.3969/j.issn.1672-5069.2018.03.014
PTIPS治疗脾切除术后并发门静脉血栓形成的门静脉高压症患者安全性和效果分析
Safety and efficacy of percutaneous transhepatic intrahepatic portosystemic shunt in management of patients with portal thrombosis after splenectomy
摘要
Abstract
Objective To investigate the safety and efficacy of percutaneous transhepatic intrahepatic portosystemic shunt(PTIPS)in management of patients with portal thrombosis after splenectomy. Methods Thirty patients with portal thrombosis after splenectomy were recruited in our hospital between January 2011 and December 2015. All patients received PTIPS,checked-up by CT scan and followed-up for(22.1±3.8)m. Results The success rate of the operation was 90%(27/30),and 3 patients failed to opening their portal vein occlusion during operation. No serious complications such as surgical related death were found in this series. The portal-systemic pressure gradient decreased from(21.5±3.4)mmHg to(13±2.8)mmHg in the 27 patients with successful operation. During the follow-up period,4 patients(13.3%)got the shunt stent occlusion,and repatency by balloon dilatation and a new stent placed instead. 2 patients(6.7%)had hepatic encephalopathy within 1 months after the operation,and were improved after appropriate treatment. 5(16.7%)patients died of hepatic failure or cerebral hemorrhage. Conclusion The application of PTIPS in the management of patients with portal thrombosis after splenectomy is effective,and the procedure is feasible and safe. Further study is still needed in the future to get the indications of this operation.关键词
脾切除术/门静脉血栓/经皮经肝肝内门体分流术/疗效Key words
Splenectomy/Portal thrombus/Percutaneous transhepatic intrahepatic portosystemic shunt/Efficacy引用本文复制引用
游玉峰,谭必勇,何小俊,胡红耀..PTIPS治疗脾切除术后并发门静脉血栓形成的门静脉高压症患者安全性和效果分析[J].实用肝脏病杂志,2018,21(3):372-375,4.基金项目
国家自然科学基金项目(编号:81660291) (编号:81660291)