眼科新进展2018，Vol.38Issue(4)：357-360,4.DOI:10.13389/j.cnki.rao.2018.0083
早产儿视网膜病变黄斑中心视网膜微血管形态特征:基于光学相干断层扫描血管成像(OCTA)的观察
Observation of central macular retinal microvascular network morphology of retinopathy of prematurity by optical coherence tomography angiography
摘要
Abstract
Objective To analyze the characteristics of central macular retinal microvascular network morphology of retinopathy of prematurity (ROP) with optical coherence tomography angiography(OCTA).Methods The 7-15 years old ROP children with laser treatment history(ROP group,25 eyes of 14 patients) and full-term children(control group,40 eyes of 20 patients) were collected by cross-sectional study.The subjects in the two groups were examined by RTVue XR Avanti-OCTA,and several parameters including the detection of the best corrected visual acuity (BCVA),central foveal thickness (CFT),foveal avascular zone (FAZ),macular superficial retinal capillary plexus (SCP) density were recorded and analyzed statistically with t test in the two groups.Results The area of FAZ in ROP group was (0.04 ± 0.05) mm2,which was significantly less than that in control group [(0.29 ± 0.08) mm2] (P ＜ 0.001).The SCP density of ROP group was 42.70％ ± 5.90％,which was significantly higher than that in the control group (35.90％ ± 6.30％) (P ＜ 0.001).The CFT in ROP group was (328.50 ± 34.90) μm,which was significantly higher than that in the control group [(236.80 ± 23.40)μm] (P ＜ 0.001).The BCVA was 0.83 ± 0.14 in ROP group and 0.85 ±0.26 in the control group,respectively,without significant difference (P ＞ 0.05).Conclusion ROP children have smaller or undefined FAZ,the thickened CFT and the increased SCP density,and the BCVA is not affected by the FAZ area and CFT in this study.关键词
早产儿视网膜病变/光学相干断层扫描血管成像/黄斑中心凹无血管区/表层视网膜血管网/黄斑中心凹视网膜厚度Key words
retinopathy of prematurity/optical coherence tomography angiography/foveal avascular zone/superficial retinal capillary plexus/central foveal thickness分类
医药卫生引用本文复制引用
冷云霞,张柳,张蒙,吴敏,蔡诚,任国梁,高宗银..早产儿视网膜病变黄斑中心视网膜微血管形态特征:基于光学相干断层扫描血管成像(OCTA)的观察[J].眼科新进展,2018,38(4):357-360,4.基金项目
广州市科技局基金项目(编号:11C33150706) （编号:11C33150706）
广东省自然科学基金(编号:S2013040012562)Science and Technology Program of Guangzhou (No:11C33150706) （编号:S2013040012562）
Natural Science Foundation of Guangdong Province (No:S2013040012562) （No:S2013040012562）
