中国动脉硬化杂志2018，Vol.26Issue(3)：273-276,4.
重度子痫前期患者分娩前后血管内皮功能的超声研究
Ultrasound study on vascular endothelial function in patients with severe preeclampsia before and after parturition
摘要
Abstract
Aim To study the flow mediated dilation (FMD) of brachial artery at different time points before and after parturition in patients with severe preeclampsia.Methods 49 cases of severe preeclampsia (study group) were examined by high-frequency color Doppler ultrasonography before parturition (28-40 weeks of pregnancy),and 1,6,24 weeks after parturition,and the right brachial artery FMD was detected.60 cases of healthy childbearing women was as the control group.The internal diameter (D1) and blood flow (Q1) of right brachial artery,and the internal diameter (D2) and blood flow (Q2) after reactive hyperemia were measured at resting state.The vessel diameter change rate (△D％) and the blood flow change rate (△Q％) were calculated.Results Before parturition,and at different time points (1,6,24 weeks) after parturition,the △D％ and △Q％ of the study group were lower than those of the control group (P＜0.001).There were no significant differences in △D％ and △Q％ inside the study group before parturition,and at different time points after parturition (1,6,24 weeks) (P＞ 0.05).Conclusion Patients with severe preeclampsia have FMD damage before parturition and continue to post parturition,and there is no obvious recovery and improvement for the 24 weeks after parturition.关键词
重度子痫前期/血流介导的内皮依赖性血管舒张功能/彩色多普勒超声Key words
Severe preeclampsia/Flow mediated dilation/Color Doppler ultrasonography分类
医药卫生引用本文复制引用
万映,关莹,南瑞霞..重度子痫前期患者分娩前后血管内皮功能的超声研究[J].中国动脉硬化杂志,2018,26(3):273-276,4.基金项目
海南省卫生计生委普通科研项目(14A210270) （14A210270）
海南省自然科学基金(814358) （814358）
