中国动脉硬化杂志2018，Vol.26Issue(3)：321-324,4.
参与负性调控胆固醇逆向转运的microRNA
MicroRNA that involves the negative regulation of reverse cholesterol transport
蒋波 1李丹 1刘亚密 2王佐 2马小峰1
作者信息
- 1. 南华大学附属南华医院,湖南省衡阳市421001
- 2. 南华大学心血管疾病研究所,湖南省衡阳市421001
- 折叠
摘要
Abstract
Strengthening the reverse cholesterol transport (RCT) has the anti-atherosclerotic effect.MicroRNA (miRNA) involves the regulation of many biological processes.Recent studies suggest that miRNA can control the ATP binding cassette transporter A1 (ABCA1) and scavenger receptor class B type Ⅰ (SR-B Ⅰ) that belong to the critical protein of RCT.Currently,it has been found that many miRNAs can inhibit the levels of SR-B Ⅰ and ABCA1 protein expression,and then inhibiting the cholesterol efflux.This paper summarizes the miRNA that involves the negative regulation of RCT.关键词
microRNA/ATP结合盒转运体A1/B类Ⅰ型清道夫受体/胆固醇逆向转运Key words
MicroRNA/ATP binding cassette transporter A1/Scavenger receptor class B type Ⅰ/Reverse cholesterol transport分类
医药卫生引用本文复制引用
蒋波,李丹,刘亚密,王佐,马小峰..参与负性调控胆固醇逆向转运的microRNA[J].中国动脉硬化杂志,2018,26(3):321-324,4.
