中国临床药理学杂志2018，Vol.34Issue(3)：282-284,3.DOI:10.13699/j.cnki.1001-6821.2018.03.028
薏苡茎叶提取物石油醚部位的体外抗肿瘤活性研究
Study on the antitumor activity of petroleum ether fractions of the extract from stems and leaves of Coix in vitro
摘要
Abstract
Objective To explore the anticancer effect of petroleum ether fraction of the extract from stems and leaves of Coix lacryma in vitro.Methods The in vitro growth inhibitory effects of different solutions of the extract of Coix stems and leaves on 3 kinds of tumor cell lines was detected by CCK-8 assay.Results Four kinds of Coix extract can inhibit the growth of the tested tumor cell lines in vitro.For the extracts of Coix stems,the half maximal inhibitory concentrations (ICs0) of petroleum ether fractions of the water extract on HeLa and ethanol extract on SGC-7901 were 51.78 and 74.44 μg · mL-1.And,for the extracts of Coix leaves,they were 45.22 and 45.91 μg · mL-1.Conclusion The petroleum ether fractions of the extract of Coix stems and leaves had better anti-tumor activity.关键词
薏苡茎叶/CCK-8/体外/抗肿瘤Key words
stems and leaves of Coix/CCK-8/in vitro/antitumor分类
医药卫生引用本文复制引用
林瑶,陆世惠,喻巧容,黄锁义..薏苡茎叶提取物石油醚部位的体外抗肿瘤活性研究[J].中国临床药理学杂志,2018,34(3):282-284,3.基金项目
国家自然科学基金资助项目(81360684) （81360684）
广西自然科学基金资助项目(2011GXNSFA018046) （2011GXNSFA018046）
广西中医药科技专项基金资助项目(GZKZ10-128) （GZKZ10-128）
广西教育厅课题基金资助项目(201106LX425) （201106LX425）
广西中医药管理局基金资助项目(gzzc1047) （gzzc1047）
广西医学科学实验中心开放基金专项资助项目(KFJJ2011-04) （KFJJ2011-04）
广西高校科学技术研究基金资助项目(KY2015LX291) （KY2015LX291）
