中国临床药理学杂志2018，Vol.34Issue(5)：604-608,5.DOI:10.13699/j.cnki.1001-6821.2018.05.032
光动力疗法治疗年龄相关性黄斑变性的临床疗效与基因多态性关联研究现状
Association between gene polymorphisms and clinical efficacy of photodynamic therapy for age-related macular degeneration
宋子扬 1赵秀丽1
作者信息
- 1. 首都医科大学 附属北京同仁医院 国家药物临床试验机构,北京 100073
- 折叠
摘要
Abstract
Age-related macular degeneration (AMD),a clinically heterogeneous disease of the macular,has become the leading cause of central blindness or low vision within the elders of Western countries.Photodynamic therapy (PDT) is the main therapy of AMD because of its high-selectivity and little damage to the surrounding tissues.However,the patient showed obviously different degrees of therapeutic response,and studies indicated that genetics exert lot of influence.This article will summarize the association between the pharmocogenetics and therapeutic response of PDT for providing genetic information for individualized PDT treatment.关键词
基因多态性/光动力/年龄相关性黄斑变性/脉络膜新生血管Key words
gene polymorphism/photodynamic therapy/age-related macular degeneration/choroidal neovascularization分类
医药卫生引用本文复制引用
宋子扬,赵秀丽..光动力疗法治疗年龄相关性黄斑变性的临床疗效与基因多态性关联研究现状[J].中国临床药理学杂志,2018,34(5):604-608,5.
