摘要
Abstract
Objective To report results of hearing screening combining automated auditory brainstem responses (AABRs)and otoacoustic emissions(OAEs)in newborns with different disease statuses and gestational ages.Methods In this study,846 newborns admitted to the neonatal ward from January 2015 to June 2017 were selected and divided in-to two groups based on the condition upon admission:i.e.critically ill(high risk group,n=416)or stable with no risk factors for hearing loss (non-critically ill group, n=430), to be compared to a control group of 178 healthy newborns. The babies were further categorized as term(gestational age≥37 weeks and body weight≥2500g,n=402)and preterm (gestational age 28-37 weeks,body weight<2500g,n=444)neonates.AABR and OAE screening was conducted when allowed by the babies'conditions,and the rate of failing was compared by AABR only,OAE only and AABR and OAE combined. Results The rate of failing OAE test was 11.78% in critically ill neonates, 7.93% in non-critically ill neo-nates and 6.87% in healthy neonates,respectively.The rate of failing AABR test was 12.38%,8.36% and 7.03%,respec-tively;while that of failing combined OAE/AABR screening was 17.67%,13.45% and 7.89%,respectively.The rates of failing OAE,AABR or combined OAE/AABR screening were all higher in critically ill neonates than in the other two groups of neonates(P<0.05).The rate of failing combined OAE/ABR screening was higher than that of failing OAE or AABR only screening (P <0.05). The rate of failing AABR test was 13.64% in full-term neonates and 19.14% in pre-term neonates, slightly higher than that of failing OAE screening (P <0.05). The rate of failing combined OAE/AABR test was 15.64% and 21.85% in full term and pre-term neonates(P<0.05),respectively.The failure rates of all three screening modes were higher in premature neonates than in full-term neonates (P< 0.05), with combined OAE/AABR screening showing consistently higher failure rates than OAE or AABR only screening(P<0.05).Conclusions Compared with single OAE or ABR screening,combined OAE/AABR screening can be an effective alternative,espe-cially in critically ill newborns and premature neonates.关键词
自动听性脑干反应/耳声发射/新生儿听力筛查/新生儿Key words
Automatic Auditory Brainstem Response/Otoacoustic Emissions/Hearing Screening/Infants分类
医药卫生
