中成药2018，Vol.40Issue(4)：875-880,6.DOI:10.3969/j.issn.1001-1528.2018.04.022
干燥温度、产地和采摘时间对洋常春藤叶中2种皂苷的影响
Effects of drying temperature, growing area and plucking time on two saponins from leaves of Hedera helix
摘要
Abstract
AIM To investigate the effects of drying temperature,growing area and plucking time on hederacoside C,α-hederin from leaves of Hedera helix L..METHODS Three batches of H.helix leaves plucked in different time from two growing areas were dried in a vacuum oven to the constant weight at 60 ℃,70 ℃,80 ℃,90 ℃ and 105 ℃,respectively.Two saponins in the processed leaves were determined by HPLC.The powders of the processed H.helix leaves of different batches were mixed with proper ratios,which were determined by least squares optimization method with constraints.RESULTS The content of hederacoside C in the processed H.helix leaves of the three batches increased while that of α-hederin decreased with increasing temperature.The relative error between measured value and desired contents of hederacoside C and α-hederin in the mixed H.helix leaves was less than 5.5％.CONCLUSION The effects of three factors on the content of two saponins in the H.helix leaves are in the order of drying temperature,growing area and plucking time.Mixing processed H.helix leaves of different quality statues reasonably can control the contents of two saponins in a certain range.关键词
洋常春藤/常春藤皂苷C/α-常春藤皂苷/干燥温度/产地/采摘时间Key words
Hedera helix L./hederacoside C/α-hederin/drying temperature/growing area/plucking time分类
医药卫生引用本文复制引用
倪力军,李等,栾绍嵘,张立国,朱美鹏,金志文,严道荣,金汉台..干燥温度、产地和采摘时间对洋常春藤叶中2种皂苷的影响[J].中成药,2018,40(4):875-880,6.基金项目
国家重大新药创制(2018ZX09721003-009-002_任务74) （2018ZX09721003-009-002_任务74）
