中国现代中药2018，Vol.20Issue(4)：382-386,5.DOI:10.13313/j.issn.1673-4890.20171029001
生白术化学成分研究
Chemical Constituents of Rhizomes of Atractylodes macrocephala
摘要
Abstract
Objective:To study the chemical constituents of the rhizomes of Atractylodes macrocephala.Methods:Repeated column chromatography on silica gel and HPLC were applied to the separation of compounds and their structures were determined by spectroscopic data analyses of MS and NMR.Results:Nine compounds were obtained and identified as atrac-tylon(1),atractylenolide Ⅰ(2),biatractylenolide(3),atractylenolide Ⅱ(4),atractylenolactam(5),atractylenolide Ⅲ(6),4R,15-epoxylatractylenolide Ⅱ(7),4R,15-epoxy-8β-hydroxylatractylenolide Ⅱ(8),and 8β,9α-dihydroxylatrac-tylenolide Ⅱ(9),respectively.Conclusion:Compound 7 was a new natural product and compound 9 was isolated from the rhizomes of A.macrocephala for the first time.关键词
白术/化学成分/4R,15-环氧白术内酯Ⅱ/8β,9α-二羟基白术内酯ⅡKey words
Rhizomes of Atractylodes macrocephala/chemical constituent/4R/15-epoxylatractylenolide Ⅱ/8β/9α-dihydroxylatractylenolide引用本文复制引用
李滢,杨秀伟..生白术化学成分研究[J].中国现代中药,2018,20(4):382-386,5.基金项目
"十二五"国家科技支撑计划(2011BAI07B08) （2011BAI07B08）
