摘要
Abstract
Objective:To evaluate the prognostic value of serum bilirubin level in patients with acute myocardial infarction (AMI) by percutaneous coronary intervention.Methods:A total of 120 patients with AMI were selected as the observation group.30 healthy persons in the same period were selected as the control group.All patients were treated with percutaneous coronary intervention (PCI) in the onset of 12 h and hospitalized.After 1 month,according to the occurrence of adverse events,the observation group was di-vided into event group and non event group.The patients were followed up for 6 months after PCI.According to the prognosis,patients were divided into survival group and death group.Serum bilirubin [total Bilirubin (TBIL),direct bilirubin (DBIL),indirect bilirubin (IBIL)],blood pressure,blood lipid and other related indexes were detected in each group,and the risk factors of death after PCI oper-ation were analyzed by Logistic regression analysis.Results:There was no significant difference in SBP,SDP,FBG and DBIL between the observation group and the control group(P>0.05),but the serum TBIL and IBIL in the observation group were significantly lower than those in the control group,and the difference was statistically significant (P<0.05).The incidence of adverse events after PCI was 40.83%,and the mortality rate of 6 months was 10.83%.The serum TBIL and IBIL in the adverse event group were significantly lower than those in the non event group.The TBIL and IBIL in the death group were significantly lower than those in the survival group, and the difference was statistically significant (P<0.05).Multivariate Logistic regression analysis showed that serum TBIL and IBIL levels were the risk factors of death in AMI patients after PCI(OR=1.158、1.473,P<0.05).Conclusion:The level of serum bilirubin is closely related to the prognosis of patients with AMI after PCI.The positive monitoring of serum levels of TBIL and IBIL after opera-tion can provide an important basis for the clinical assessment of the risk of adverse events and the survival of the prognosis.关键词
急性心肌梗死/血清胆红素/不良事件/死亡风险/预后价值Key words
Acute myocardial infarction(AMI)/Serum bilirubin/Adverse events/Death risk/Prognostic value分类
医药卫生