重庆医学2018，Vol.47Issue(13)：1758-1762,5.DOI:10.3969/j.issn.1671-8348.2018.13.017
玉屏风散联合抗组胺药治疗慢性荨麻疹有效性和安全性的Meta分析
Meta-analysis on effect and safety of Yupingfeng Powder combined with antihistamines for chronic urticaria
摘要
Abstract
Objective To evaluate the effect and safetyof Yupingfeng Powdercombined with antihistamines for the treatment of patients with chronic urticaria.Methods Searched all randomized controlled trials (RCTs)of Yupingfeng Powder for treatment of chronic urticaria from the databases of CENTRAL,Pubmed,Embase,CNKI,CBM,VIP and Wanfang.Two researchers independently searched the literature and used the Cochrane system evaluation method to evaluate the quality of the study,and used RevMan 5.3 for meta-analysis.Results A total of 10 RCTs involving 964 patients were included in this study.Meta-analysis showed that compared with antihistamines alone,Yupingfeng Powder combined with antihistamines could improve the clinical effective rate (OR=2.83,95 ％ CI:1.89-4.25,P ＜ 0.01),reduce relapse rate (OR =0.13,95 ％ CI:0.07-0.24,P＜0.01) and reduce the incidence of adverse reactions (OR=0.40,95％CI:0.19-0.83,P=0.01).Conclusion Yupingfeng Powder combined with antihistamines has superior clinical effective rate,lower recurrence rate and incidence of adverse reactions.关键词
慢性荨麻疹/玉屏风散/Meta分析/系统评价/随机对照试验Key words
chronic urticaria/yupingfeng powder/systematic review/meta-analysis/randomized controlled trials分类
医药卫生引用本文复制引用
沈萃萃,吕萌,卢传坚..玉屏风散联合抗组胺药治疗慢性荨麻疹有效性和安全性的Meta分析[J].重庆医学,2018,47(13):1758-1762,5.基金项目
广东省科技攻关计划项目(2014A020221040). （2014A020221040）
