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金纳米星/双锥的可控制备、光热转换及体外光热治疗

吴頔 樊淼 张露云 邢晶晶 吕树芳 曾乐勇

发光学报2018,Vol.39Issue(3):280-286,7.
发光学报2018,Vol.39Issue(3):280-286,7.DOI:10.3788/fgxb20183903.0280

金纳米星/双锥的可控制备、光热转换及体外光热治疗

Controllable Synthesis, Photothermal Conversion and in vitro Photothermal Therapy of Gold Nanostars/Nanobipyramids

吴頔 1樊淼 1张露云 1邢晶晶 1吕树芳 1曾乐勇1

作者信息

  • 1. 河北大学 化学与环境科学学院,河北 保定 071002
  • 折叠

摘要

Abstract

Using seed-growth method,gold nanostars and gold nanobipyramids were synthesized,re-spectively,and they were characterized by transmission electron microscope and ultraviolet-visible (UV-Vis) spectrophotometer. Moreover,the photothermal conversion,biocompatibility and in vitro photothermal therapy(PTT) of gold nanostars and gold nanobipyramids were evaluated. The results show that the UV-Vis absorption peaks of gold nanostars and gold nanobipyramids are located at about 808 nm and 815 nm,and the photothermal conversion efficiency is calculated to be 48.43% and 53.68%. The cell experiments indicate that the gold nanostars and gold nanobipyramids have good biocompatibility,and the viabilities of MCF-7 cells incubate with gold nanostars and gold nano-bipyramids are decreased to be about 22.54% and 13.73%,after they are irradiated by 808 nm la-ser for 5 min, respectively. Furthermore, compared with the gold nanostars, the gold nanobipyra-mids have more excellent PTT performance,which could be good candidate as safe and high-efficient nanoprobe material for PTT in tumors.

关键词

金纳米星/金纳米双锥/光热治疗

Key words

gold nanostars/gold nanobipyramids/photothermal therapy

分类

数理科学

引用本文复制引用

吴頔,樊淼,张露云,邢晶晶,吕树芳,曾乐勇..金纳米星/双锥的可控制备、光热转换及体外光热治疗[J].发光学报,2018,39(3):280-286,7.

基金项目

国家自然科学基金(51772074,U1732127) (51772074,U1732127)

河北省科技厅重点基础研究项目(17961302D) (17961302D)

河北省教育厅青年拔尖人才项目(BJ2017002) (BJ2017002)

河北大学大学生创新创业训练计划(2017145)资助项目 Supported by National Natural Science Foundation of China(51772074,U1732127) (2017145)

Key Basic Research Foundation of Science&amp ()

Technology Department of Hebei Province(17961302D) (17961302D)

Youth Top-notch Talents of Education Department of Hebei Province(BJ2017002) (BJ2017002)

Undergraduate&apos ()

Innovation and Entrepreneurship Training Program of Hebei University(2017145) (2017145)

发光学报

OA北大核心CSCDCSTPCD

1000-7032

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