福建农业学报2018，Vol.33Issue(2)：109-113,5.DOI:10.19303/j.issn.1008-0384.2018.02.001
我国部分地区鸭1型甲肝病毒流行株遗传变异分析
Epidemiology and Genetic Variation of Duck Hepatitis A Virus Type 1 Circulating in Some Regions of China
摘要
Abstract
The epidemic prevalence and molecular variation of duck hepatitis A virus type 1 (DHAV-1) were investigated.Three-hundred-twenty-seven clinical samples collected in 2015-2016 from Fujian and surrounding provinces were used for the virus detection and isolation.Thirty-five of these samples (10.7％) were found to be pusitive for DHAV-1.From the 35 positive specimens,23 strains were isolated,mainly from shelducks and mule ducks of less than 30-day-old.The sequence analysis on VP1 gene of the 23 isolates showed 93.3％-99.9％ homology,and the strains could be divided into 2 subgroups with a genetic distance of 0.06.Among them,18 isolates clustered in a currently prevalent subgroup which contains the virus (MPZJ1206) causing yellowed-pancreas in ducklings.On the other hand,all 23 isolates shared merely 91.3-96.2％ nucleotide sequence homology with the strain used for vaccination abroad and domestically.It appeared that genetic variations existed among the various DHAV-1 strains.关键词
鸭1型甲肝病毒/VP1基因/变异分析Key words
duck hepatitis A virus type 1/VP1 gene/variation analysis分类
农业科技引用本文复制引用
傅光华,黄瑜,陈翠腾,温名根,施少华,陈红梅,万春和,傅秋玲,程龙飞,刘荣昌..我国部分地区鸭1型甲肝病毒流行株遗传变异分析[J].福建农业学报,2018,33(2):109-113,5.基金项目
福建省自然科学基金项目(2015J01113) （2015J01113）
福建省科技计划项目——省属公益类科研院所基本科研专项(2015R1023-3) （2015R1023-3）
现代农业(水禽)产业技术体系建设专项(CARS-42) （水禽）
福建省农业科学院青年英才计划项目(YC2015-13) （YC2015-13）
