广西医科大学学报2018，Vol.35Issue(4)：487-490,4.DOI:10.16190/j.cnki.45-1211/r.2018.04.016
92例过敏性紫癜患儿的临床特征及合并肾损害的危险因素分析
Analysis of clinical features and risk factors of renal injury in 92 children with Henoch Schonlein purpura
摘要
Abstract
Objective::To investigate the clinical features and related factors of renal injury in 92 children with Henoch Schonlein purpura (HSP).Methods:Clinical data of 92 children with HSP in our hospital from August 2014 to August 2016 were retrospective analyzed.The clinical characteristics and risk factors for renal injury were analyzed.Results:HSP often occurred in 7-14 years old children,accounting for 57.61％.The male and female ratio in the patients was 1.36 ∶ 1.HSP often occurred in spring and winter.Children with HSP were accompanied by skin purpura that was obvious in both lower extremities.51.09％ of HSP children were accompanied by gastrointestinal symptoms,mainly abdominal pain,abdominal distension and vomiting,and 45.65％ children were arthralgia.Of 92 HSP children,there were 35 cases combined with renal damage,accounted for 38.04 ％.Univariate and multivariate logistic regression analysis revealed that age ≥ 7 years,recurrent rash,increased plasma fibrinogen (FIB) level,decreased platelet (PLT) count and high-density lipoprotein (HDL) level were independent risk factors for renal injury in HSP children (P＜0.05).Conclusion:HSP is a common disease in children that is characterized by typical symptoms.Older than 7 years,recurrent rash,increased plasma FIB,and decreased PLT and HDL are independent risk factors for renal injury in HSP children.关键词
过敏性紫癜/流行病学/肾损害Key words
Henoch Schonlein purpura/epidemiology/renal injury分类
医药卫生引用本文复制引用
刘丽君..92例过敏性紫癜患儿的临床特征及合并肾损害的危险因素分析[J].广西医科大学学报,2018,35(4):487-490,4.基金项目
2015年甘肃省卫生行业科研计划项目(No.GSWSKY-2015-43) （No.GSWSKY-2015-43）
